Protein Alignment PLPPR1 and laza

DIOPT Version :10

• Sequence 1: NP_060223.2
• Gene: PLPPR1 / 54886
• HGNCID: 25993
• Length: 325
• Species: Homo sapiens
• Sequence 2: NP_649391.1
• Gene: laza / 40468
• FlyBaseID: FBgn0037163
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 82/306 - (26%)
• Similarity: 125/306 - (40%)
• Gaps: 52/306 - (16%)

Human    40 TFQVHIQGFFCQDGDLMKPYPGTEEESFITPLVLYCVLAATPTAIIFIGEISMYFIKSTRESLIA 104
            ||:   :||||.|..:..||    ::..||..:|..::...|...:.:.|| |...|..|..|
  Fly     3 TFK---RGFFCSDLSIRYPY----KDCTITVPMLLLMMLLLPMLFVAVVEI-MRICKRFRTRL-- 57

Human   105 QEKTILTGECCYLNPLLRRIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNY----T 165
                           ..|.:.|....|:||..||.:.....:...|.|.|:|...|:|..    :
  Fly    58 ---------------YFRNLWRAEATFSFGFIATYLTTELAKHAVGRLRPHFFHGCQPRLDDGSS 107

Human   166 SADCQAHHQFI-----NNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITSTIKTKSS- 224
            .:|.|....::     .|.|:.|   ..|.:...||||.|::||.||.:...:|:....:.:..
  Fly   108 CSDLQNAELYVEQFHCTNNNLST---RQIRELHVSFPSAHSSLSFYSMVLLALYVHGVWRGRGGV 169

Human   225 RLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTA----VALFLGMCVVHNFKGTQGS 285
            |:.:.||....|..|....|:||::|.:|.|||:||.:||..    .|.::|..:......|...
  Fly   170 RVLRHVLQFLLLMAALCVSLSRVADYWHHWSDVLAGALLGVTYAAITAAYVGNLLRRQTSSTGRI 234

Human   286 PSKPKPEDPRGVPLMAFPRIESPLETLSAQNH------SASMTEVT 325
            |............|||    ::...|.||:.|      |||||..|
  Fly   235 PPSLNYSHHLHHQLMA----DNNNSTASAKVHFLAAAASASMTTTT 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLPPR1	NP_060223.2	PAP2_wunen	123..272	CDD:239479	46/162 (28%)
laza	NP_649391.1	PAP2_wunen	62..217	CDD:239479	45/157 (29%)