DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rlim and gol

DIOPT Version :9

Sequence 1:	NP_001016091.1	Gene:	rlim / 548845	XenbaseID:	XB-GENE-492020	Length:	639	Species:	Xenopus tropicalis
Sequence 2:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	49/158 - (31%)
Similarity:	75/158 - (47%)	Gaps:	32/158 - (20%)

- Green bases have known domain annotations that are detailed below.

Frog   512 EEGSNVSTSSARREGRNSRGGVTFEESGSLPFLSLA-----------------QFFLLNEDDDDQ 559
            ::|.||:.|..  |||.....::.....|:.|:|::                 |.|...:..|.|
  Fly   208 DKGYNVTISII--EGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQ 270

Frog   560 PRGL---TKEQIDNLSTR--NFGENDALKT--CSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLS 617
            .|.|   ||:.|..:.|:  .|.:...|.:  |::||..|...:.:|.|||.||:|.:|||.||.
  Fly   271 SRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLI 335

Frog   618 ENSTCPICRRAVL------VAGNRESIV 639
            |:.|||:|:..||      ..|:.|||:
  Fly   336 EHRTCPMCKLDVLKFYGYVFLGSEESIL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rlim	NP_001016091.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..403
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	467..534		7/21 (33%)
		zf-RING_2	584..626	CDD:290367	20/43 (47%)
		PDZ-binding. /evidence=ECO:0000255	636..639		2/2 (100%)
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	3/8 (38%)
		UPF0233	226..>258	CDD:299753	3/31 (10%)
		zf-RING_2	301..344	CDD:290367	20/42 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920