Protein Alignment rlim and Rlim

DIOPT Version :10

• Sequence 1: NP_001016091.1
• Gene: rlim / 548845
• XenbaseID: XB-GENE-492020
• Length: 639
• Species: Xenopus tropicalis
• Sequence 2: NP_001020063.1
• Gene: Rlim / 317241
• RGDID: 1559832
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 420/668 - (62%)
• Similarity: 478/668 - (71%)
• Gaps: 94/668 - (14%)

 Frog     1 MESADSAGKGSTEQSESQRQSQMDRLDREEAFYQFVNNLNEDDYRLMRDNNLLGTPGEITKEELL 65
            ||::||..||| :||.:||:|||||||||||||||||||:|:||||||||||||||||.|:||||
  Rat     1 MENSDSNDKGS-DQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELL 64

 Frog    66 RRLQQIKEGPPQPSTEGTRGDPVSASGDPAEDSSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRA 130
            |||||||||||..|::..|      :|:.::|.||.||||||||||||:||||||||||||||||
  Rat    65 RRLQQIKEGPPPQSSDENR------AGESSDDVSNSDSIIDWLNSVRQSGNTTRSGQRGNQSWRA 123

 Frog   131 VSRTNPNSGDFRFSLEINVNR-----TSGNPSMPSLEQSSEMPGAEDMEVSSQGENE---NEPEP 187
            |||||||||||||||||||||     ||.|.:.||..:.|    .|.||.|||.:.|   :|...
  Rat   124 VSRTNPNSGDFRFSLEINVNRNNGSQTSENENEPSTRRLS----VESMESSSQRQMESHASESTS 184

 Frog   188 VAPRVAQAEVTE--EAPVQRGQRRARSRSPDQRRTRARTDRSRSPLHQAVEPPIRRAQHSSSQTV 250
            ..|..|:...||  |.|:.|||||||||||:.||||||.:|||||||..:|.| |||
  Rat   185 ARPSRAERNSTEALEVPLTRGQRRARSRSPEHRRTRARAERSRSPLHPTIEIP-RRA-------- 240

 Frog   251 DASSTEEAEGSSRTRHHVSSQMQNSSSSNETEGSSRTRQHITARQQALGTE-------GQSQSQT 308
                          .|::|.|.......||.|||||||.|:|.|||..|.|       ..|.|:
  Rat   241 --------------HHNISPQTLEQPLENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSR- 290

 Frog   309 QTQSQSQTQTQSQTQSQSTVHLSNPESRSSSQPPQTDSSSNAETTGTGQRPPTIVLDLQVRRVRP 373
                                   ||...:||    :|:.||:|::|:||||||||||||||||||
  Rat   291 -----------------------NPSQGTSS----SDTGSNSESSGSGQRPPTIVLDLQVRRVRP 328

 Frog   374 GDYRQRDSIANRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLS 438
            |:||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   329 GEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLS 393

 Frog   439 ETTSVAIQTMLRQIMTGFGELSYFMYNDNDTDPNNPTPVSPPAAVPGEAQN----------LVSP 493
            ||||||||||||||||||||||||||:|:|::|:  ..||.......|::|          ..|.
  Rat   394 ETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPS--ASVSSRNTERAESRNGRGSSGAGNSSASS 456

 Frog   494 EPPAPIVEPPEPVAPVESEEGSNVSTSS--ARREGRNSRGGVTFEESGSLPFLSLAQFFLLNEDD 556
            ..|:|........:..:..||::....|  :||:||: |..|.|:||||||||||||||||||||
  Rat   457 SSPSPSSNGESSESSSDLFEGTSEGGPSGPSRRDGRH-RAPVAFDESGSLPFLSLAQFFLLNEDD 520

 Frog   557 DDQPRGLTKEQIDNLSTRNFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENST 621
            :||||||||||||||:.|:||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 EDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENST 585

 Frog   622 CPICRRAVLVAGNRESIV 639
            |||||||||.:|||||:|
  Rat   586 CPICRRAVLSSGNRESVV 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rlim	NP_001016091.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28		17/26 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	67..403		188/352 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	467..534		17/78 (22%)
		RING-H2_RNF12	583..633	CDD:438336	48/49 (98%)
		PDZ-binding. /evidence=ECO:0000255	636..639		2/2 (100%)
Rlim	NP_001020063.1	RING-H2_RNF12	547..597	CDD:438336	48/49 (98%)