DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rlim and dsc1

DIOPT Version :9

Sequence 1:	NP_001016091.1	Gene:	rlim / 548845	XenbaseID:	XB-GENE-492020	Length:	639	Species:	Xenopus tropicalis
Sequence 2:	NP_595266.2	Gene:	dsc1 / 2541251	PomBaseID:	SPBC947.10	Length:	695	Species:	Schizosaccharomyces pombe

Alignment Length:	340	Identity:	59/340 - (17%)
Similarity:	97/340 - (28%)	Gaps:	140/340 - (41%)

- Green bases have known domain annotations that are detailed below.

Frog   415 RAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYNDNDTDPNNPTPVSP 479
            :||:..|::...:....::..|.....|||..:::..:|.....|:..:...|...|       |
pombe   362 QAGLDAYIAIFFLSTNAVIEKGYLPFVSVAFLSLVPSVMFTMRYLALILRVQNSNMP-------P 419

Frog   480 PAAVP------------GEAQNLVSPEPPA--------PIVEPP----EPVAPVESEE------- 513
            ||..|            ..|.|..||..|:        ..|.||    :|:...|.::
pombe   420 PAPRPVTNNSSNNNTNQSNASNENSPNAPSAANDNTETTTVNPPQEDDQPMTQHERDQRDWSAVC 484

Frog   514 -----------------------------GSNVSTSSA---------RREGRNSRGGVTFEESGS 540
                                         .:.:.||.:         .::|.:.....|:....|
pombe   485 LRFYFIILVVCIASLYSAFWPVIYRFYFISALIFTSYSFWIPQIIQNVKQGTSRSFTWTYILGAS 549

Frog   541 L--PFLSLAQFFLLNEDDDDQPRGLTKEQI-------------------DNLSTRNF-------- 576
            :  .:|.||.|.     |.:...|...:..                   |.|..|.|
pombe   550 VLRLYLPLAIFI-----DSELILGFPPKYFFALGLVLWMLFQVLVLLVQDTLGPRFFLPKKFFLS 609

Frog   577 ---------GENDALK-------TCSVC---ITEYTEGNKLRK-----------LPCSHEYHVHC 611
                     .:.|.|:       .|.:|   |...:.|:.|..           .||.|.||..|
pombe   610 SPVYDYHPVIQQDDLEAFMRDANVCPICMQPIELVSTGSTLNPASMMVRRNYMLTPCHHLYHRQC 674

Frog   612 IDRWLSENSTCPICR 626
            :.:|:...|.||:||
pombe   675 LLQWMETRSICPVCR 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rlim	NP_001016091.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..403
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	467..534		19/135 (14%)
		zf-RING_2	584..626	CDD:290367	15/55 (27%)
		PDZ-binding. /evidence=ECO:0000255	636..639
dsc1	NP_595266.2	zf-RING_2	632..689	CDD:290367	15/56 (27%)
dsc1	NP_595266.2	zf-rbx1	<633..689	CDD:289448	15/55 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910