DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rlim and plr-1

DIOPT Version :9

Sequence 1:	NP_001016091.1	Gene:	rlim / 548845	XenbaseID:	XB-GENE-492020	Length:	639	Species:	Xenopus tropicalis
Sequence 2:	NP_499473.2	Gene:	plr-1 / 176575	WormBaseID:	WBGene00023404	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	317	Identity:	66/317 - (20%)
Similarity:	95/317 - (29%)	Gaps:	116/317 - (36%)

- Green bases have known domain annotations that are detailed below.

Frog   404 GGFRRTFSRSERAGVRTYVSTIRI--PIRRILNTGLSETTSVAIQTMLRQIMTG---------FG 457
            |.|....|..|..|....||:.|.  ..|:.|:..:.|...|.....:.:.:||         |.
Worm    64 GTFSPVGSNYETGGDIVQVSSFRACDARRKGLDNTVFEHVPVVFYDDVEKFLTGCVALDNQARFA 128

Frog   458 ELSYFMYNDNDTDPNNPTPVSPPAAVPGEAQNLVSPEPPAPIVEPPEPVAPVESEEGSNVSTSSA 522
            |.|..|                 |.:.|.|..:.....|..|.....||..::.|:     |...
Worm   129 EKSGAM-----------------ALIVGPASRVERTTRPMMIGGSKIPVIVLDDEQ-----TERL 171

Frog   523 RREGRNS--RGGVT-----FEESGSLPFLSLAQF---------------------FLLNEDDDDQ 559
            |.|.|::  ||.||     |.:......|.|..|                     .|:......|
Worm   172 RSELRSASERGAVTKLRISFIDEKPTKVLKLQVFRPTVLNITLLGLLIILIVFVSLLVVVKIRCQ 236

Frog   560 P--------RGLTKEQIDNLSTRNF---------------------------------------- 576
            |        |.|.:..:..:..|:|
Worm   237 PTMHRELWLRALARTALTKMEIRSFQKEKNVEAGQKKKTSSTFARLKQHRSSSSRHSSYLAVFGS 301

Frog   577 -------GENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICR 626
                   ..:.|.:.|.:|:.||.||.:||.|.|.||:|..|:|.||.....||:|:
Worm   302 LTSVAQSSSHSAQERCVICLEEYEEGTELRVLFCGHEFHPKCVDPWLLSKRRCPLCQ 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rlim	NP_001016091.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..403
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	467..534		14/68 (21%)
		zf-RING_2	584..626	CDD:290367	19/41 (46%)
		PDZ-binding. /evidence=ECO:0000255	636..639
plr-1	NP_499473.2	zf-rbx1	305..358	CDD:289448	20/52 (38%)
plr-1	NP_499473.2	zf-RING_2	317..357	CDD:290367	19/39 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920