Protein Alignment TOR4A and tor-2

DIOPT Version :9

• Sequence 1: NP_060193.2
• Gene: TOR4A / 54863
• HGNCID: 25981
• Length: 423
• Species: Homo sapiens
• Sequence 2: NP_502683.2
• Gene: tor-2 / 189606
• WormBaseID: WBGene00006598
• Length: 310
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 64/299 - (21%)
• Similarity: 124/299 - (41%)
• Gaps: 48/299 - (16%)

Human   148 YDLDGLEKALQRAVFGQPAAVSRIVALMRDYLATHVHSRPLLLALHGPSGVGKSHVGRLLARH-F 211
            ::...|.|.....:|||......:|..::.:.......:||:|:.||.:|.||::|..::..: :
 Worm    17 FNYHALYKDFDNKIFGQHLMAESVVHSIKSHWHNEHSQKPLVLSFHGGTGTGKNYVTEIIVNNTY 81

Human   212 RSVLEDSALVLQYHARHHCPEARAAQDCREELARRVADVVARAEAEEKTPLLVLDDVELMPRPLL 276
            ||.:. |..|..:.|.::.|..:..:|.:.||    .|.:.|:....:..:.:.|:.:.:...|:
 Worm    82 RSGMH-SPFVNYFVATNNFPNKKYIEDYKLEL----KDQLIRSARRCQRSIFIFDETDKLQSELI 141

Human   277 DELHGFLQPQRS---HHFHNAIYVLLSGAGGAEVTRFVLQNASRALPLRPDGFRSAEAAAAQAEE 338
            ..:..||....:   ..|...|::.||..|..|:....|::              .|....:::.
 Worm   142 QVIKPFLDYYPAVFGVDFRKTIFIFLSNKGSKEIANIALEH--------------HENGKIRSQL 192

Human   339 DL----RASLLAVLSREHPLWQAAAI--------VPFLLLDKRDVVSCF--------RDEMAGEG 383
            :|    |..:|:..:.|..|.....|        :|||.|.|..|..|.        |.::|.:|
 Worm   193 ELKHFERTLMLSAFNEEGGLRNTDMISNQLIDHFIPFLPLSKFYVSQCIQVHLRKRGRHDLAKDG 257

Human   384 FFPDQARAENLAAQLSFYRVAGREFAVTGCKQVVATVNL 422
            .|     .:.:...|.|:..:.:.|:.:|||:|.|..:|
 Worm   258 EF-----MQRVLDSLEFFPESSKIFSSSGCKRVNAKTDL 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TOR4A	NP_060193.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	47..68
		P-loop_NTPase	149..253	CDD:304359	25/104 (24%)
		AAA	186..>290	CDD:214640	24/107 (22%)
tor-2	NP_502683.2	Torsin	5..130	CDD:148114	26/117 (22%)
		AAA	55..179	CDD:214640	30/128 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161454014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2170
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10760
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.800