DRSC/TRiP Functional Genomics Resources

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Protein Alignment CC2D1A and ccct-1

DIOPT Version :10

Sequence 1:NP_060191.3 Gene:CC2D1A / 54862 HGNCID:30237 Length:951 Species:Homo sapiens
Sequence 2:NP_001359623.1 Gene:ccct-1 / 173244 WormBaseID:WBGene00012578 Length:781 Species:Caenorhabditis elegans


Alignment Length:839 Identity:251/839 - (29%)
Similarity:383/839 - (45%) Gaps:144/839 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    41 DEELEAEFLAL--------------VGGQPPALEKLKGKGPLPMEAIEKMASLCMRDP------- 84
            |.||.||..|:              ..|.|||   .:|: |.|...    |::...||       
 Worm    17 DAELLAELAAIQEEEMGRVSRPAAPARGAPPA---ARGR-PAPAAP----ANVPGLDPRLLAAAL 73

Human    85 DEDEEEGTDEDDLEADDDLLAELNEVL--GEEQKASETPPPVAQPK---PEAPHPGLETT----- 139
            .::..:|.|| :||.|:|||.|||.::  |....|:.|.|..|.|:   |..|.|.....     
 Worm    74 ADNHGDGGDE-ELEMDEDLLNELNGLVGGGGGGGAAPTVPTRAAPRAPGPSGPPPSASAPNSQLG 137

Human   140 -LQERLALYQTAIESARQAGDSAKMRRYDRGLKTLENLLASIRKGNAIDEADIP--PP----VAI 197
             |::....|..|.:||.|||:..|.|||.|.:..|..|:.::.:|..|||::||  ||    .|.
 Worm   138 HLKQLHVYYMKAHKSAEQAGEGPKARRYKRAVDKLVELIRAVERGKTIDESEIPVAPPNFSSAAA 202

Human   198 GKGPASTPTYSPAPTQPAPRIASA-----------PEPRVTLEGPSATAPASSPGLAKPQMPPGP 251
            ...|...||..||...|||.|..|           |:.:.:...|:|.||   |...:|..|   
 Worm   203 EPLPPPAPTAQPAHHPPAPPIRQAAHAAESSPPPIPQRKSSAPAPTAAAP---PATKEPTDP--- 261

Human   252 CSPGPLAQLQSRQRD-YKLAALHAKQQGDTTAAARHFRVAKSFDAVLEALSR--GEPVDLSCLPP 313
             ....:.::...:|| :|..|..|....|..:|.....:||:||..:.||:.  .:.:|::.:||
 Worm   262 -KKAAIYRILHHRRDLHKQNARAAIADKDKESAKESVEMAKAFDQAIAALNECSADEMDMNDVPP 325

Human   314 -PPDQLPPDPPSPPSQPPTPATAPSTTEVPPPPRTLLEALEQRMERYQVAAAQAKSKGDQRKARM 377
             ||....|.||.|.: |||.|          .|...:|.|:||.:|:|..|.:||::|::||.:|
 Worm   326 SPPPYRKPAPPQPQA-PPTSA----------GPLGFIEELQQRQQRFQKMAEKAKTEGNERKMKM 379

Human   378 HERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLEATKPTQQSLVGVLETAMKLANQDEGP 442
            :.|:..|:.:||:..|.|:.|:|.|||..|...|:.                             
 Worm   380 NMRLAGQFDEAIKEAKRGKLVNVGELPSLPDMGPLP----------------------------- 415

Human   443 EDEEDEVPKKQNSPVAPTAQPKAPPSRT-PQSGSAPTAKAPPKATSTRAQQQLAFLEGRKKQLLQ 506
                   |:......||....:.||... |.:.|....|       :|.|.||.||..|:.|..|
 Worm   416 -------PQTAPGQAAPKLHQRPPPQEVGPLAPSGVEGK-------SRNQGQLEFLLERQAQFKQ 466

Human   507 AALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDITKVPPAPVNKDDFALVQRP----GPG 567
            ||:.||.:.|||.||.:|.:.||.:.|::|::.||||.| |..|.|......:...:|    ...
 Worm   467 AAIHAKSRGDVEAAKKYLVEMKGFDKMIQAAQAGLPVSI-KATPIPPQAQTASTTLQPRIQSAAA 530

Human   568 LSQEAARRYGE----LTKLIRQQHEMCLNHSNQFTQLGNITETTKFEKLAEDCKRSMDILKQAFV 628
            .|.......||    |.|.:.:|......:..:||:||::.:...||...:..|:.:.::::...
 Worm   531 SSSTGVENRGEKLSLLEKTLIEQVRSAETNQMRFTRLGDVGKVRLFEGWGKVAKQDLLLVREVAK 595

Human   629 RGLPTPTARFEQRTFSVIKIFPDLSSNDMLLFIVKGINLPTPPGLSPGDLDVFVRFDFPYPNVEE 693
            |||..|...:|.|......:||||:.:.:.|.||...::|.|.|......::|:::.||....:.
 Worm   596 RGLQVPKFHYEMRQIPSADLFPDLADDVIELTIVSCRDVPLPSGYETHHANLFIKYTFPAVVNDL 660

Human   694 AQKDKTSVIKNTDSPEFKEQFKLCI-------NRSHRGFRRAIQTKGIKFEVVHKGGLFKTDRVL 751
            .|..||.:|..|.||:|.|...|.|       ::..|.|:|.    |:||||..|||..::|::|
 Worm   661 PQTGKTKLIAGTASPDFGESIMLNIGSGKSRNSKLQRTFKRG----GLKFEVFQKGGFMRSDKLL 721

Human   752 GTAQLKLDALEIACEVREILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVID 810
            ||.:.||:.||.:.|:.|.|.:.|||:..||.|...||||:|:...:.:...::||::|
 Worm   722 GTCEWKLEKLEHSAEMEESLPLKDGRKAVGGLLSAKVRIRQPIGDAKAQHIAQKWLILD 780

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CC2D1ANP_060191.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 80..139 23/70 (33%)
PHA03247 <116..477 CDD:223021 110/391 (28%)
DM14 140..195 CDD:128928 23/60 (38%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..266 26/97 (27%)
DM14 257..310 CDD:128928 14/55 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 306..346 13/40 (33%)
DM14 349..407 CDD:128928 24/57 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 437..491 9/54 (17%)
DM14 494..552 CDD:128928 27/57 (47%)
C2_Freud-1 652..809 CDD:176072 56/163 (34%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 818..841
chemoreceptor_sensor 851..918 CDD:444710
ccct-1NP_001359623.1 DM14 146..194 CDD:128928 20/47 (43%)
DM14 351..409 CDD:128928 24/57 (42%)
DM14 454..512 CDD:128928 27/58 (47%)
C2_Freud-1 621..779 CDD:176072 55/161 (34%)
Blue background indicates that the domain is not in the aligned region.

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