Protein Alignment BCAS3 and rudhira

DIOPT Version :10

• Sequence 1: NP_001340073.1
• Gene: BCAS3 / 54828
• HGNCID: 14347
• Length: 958
• Species: Homo sapiens
• Sequence 2: NP_001368979.1
• Gene: rudhira / 32136
• FlyBaseID: FBgn0266019
• Length: 2162
• Species: Drosophila melanogaster
• Alignment Length: 1102
• Identity: 371/1102 - (33%)
• Similarity: 509/1102 - (46%)
• Gaps: 269/1102 - (24%)

Human     5 MATDSPRR--------------------PSRCTGG--------VVVRPQAVTEQSYMESVVTFLQ 41
            |:.|||||                    .|..|||        .:|.||.|:::|.::|.:.|:.
  Fly     1 MSADSPRRHPSGVVGSGIGLGSGSGTGLGSGSTGGSKSGAAVPAIVPPQTVSDRSILDSAIGFIN 65

Human    42 DVVPQAYSGTPLTEEKEKIVWVRFEN-ADLNDTSRNLEFHEIHSTGN-EPPLLIMIGYSDGMQVW 104
            ||   ..:..|:.:.|:.|.|.|||. ||::| .|..:..|:.  || .||||:::||..|:|||
  Fly    66 DV---TLANQPVQDPKDTITWARFETCADVSD-PRFGDDWELE--GNAAPPLLLILGYGLGVQVW 124

Human   105 SIPISGEAQELFSVRHGPIRAARILPAPQFGA---------QKCDNFAEKRPLL----------- 149
            :||.:|||.|:.|.|||.:.|.|:||.|...|         :..|:|||||||:
  Fly   125 AIPANGEAVEVLSWRHGVVTALRVLPTPATAAALDENGRADEPVDSFAEKRPLVAFVDGGSAAAS 189

Human   150 ----------------GVCKSIGSSG--------TSPPYCCVDLYSLRTGEMVKSIQFKTPIYDL 190
                            ||....||.|        .|..:..|:..||:||..||:|:||..:.|:
  Fly   190 GLLAGSSGLGLGGGGGGVTTVGGSVGGVSGIGVSASAQFSAVNFMSLKTGVQVKTIKFKNAVLDI 254

Human   191 HCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRG 255
            ..|:..:|:...|:||.||:.|...:..:|:|||.||.|.||||||.|||||||:||:...:|.|
  Fly   255 QANRSAVVITFHERIAVFDARTLEDRLTITTCYPSPGINPNPIALGPRWLAYAEHKLLHSKRSGG 319

Human   256 GACGDNIQSYTATVISAAKTLKSGLTMVG-KVVTQLTGTLP-SGVTEDDVAIHS-----NSRRSP 313
            |..|:.:.||||||::|||:|..||...| :|...||||.. ||.:....:..|     ::::|
  Fly   320 GCDGEGVPSYTATVLNAAKSLSKGLREFGEQVAAGLTGTTAGSGASSKSSSFDSASGGPDAKQS- 383

Human   314 LVPGIITVIDTE------TVGEGQVLVS---EDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTT 369
               |::|:||.:      :...|..|.|   .....|.|||||.||.:.:..|.|::|||||:|.
  Fly   384 ---GVVTIIDVKHPVKDYSPTSGTPLSSTAGSQGGGDPIVAHFVAHSEALVAMEFDSSGMLLLTA 445

Human   370 DTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPI 434
            |..|||||||::..||...|..||||||.||||:|.||||.|.||.|.||..|||||||:|||||
  Fly   446 DRRGHDFHVFRVQPHPVGPSLAAVHHLYVLHRGDTSAKVQHIAFSLDSRWAAVSTLRGTTHVFPI 510

Human   435 NPYGGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHANQQ 499
            .||||...||||.|..|||::|||.:||||                ...|.||||
  Fly   511 TPYGGAMGVRTHTSLHVVNKLSRFHRSAGL----------------GADGRSSSP---------- 549

Human   500 INTKELIGSFLNVGRAYRLIGISGLSGKLNSQDSYNNFTNNNPGNPRLSPLPSLMVVMPLAQIKQ 564
                               |..|..:..:.|...|:        ||.|.|.|...||.||||::|
  Fly   550 -------------------ISHSESTTFVQSLQPYH--------NPTLPPYPRPSVVQPLAQLRQ 587

Human   565 PMTLGTITKRT-------GPYLFGAGC--------FSIKAPCKVKPPPQISPSKSMGGEFCVAAI 614
            |.|||:.....       |..:.|:|.        ..:.:..:.:.....|.|...|....|.:|
  Fly   588 PFTLGSPPGSAGLGGGVGGGGVMGSGVSAGGHGVGVGVGSNSQRQRQRLSSLSDDSGKPLSVCSI 652

Human   615 FGTSRSWFANNAGLKREKDQSKQ-VVVESLYIISCYGTLVEHMMEPRPLS--TAPKISDDTPLEM 676
            |..||||........||:....| ..|:||::::.:|.|:::.::.:..|  ...||.||||:|:
  Fly   653 FAKSRSWLLEPPMATREQPHRVQRKAVDSLFVMAGHGALIQYDLDTKLASHVAKEKICDDTPIEL 717

Human   677 MTSPRASWTLVRTPQWN-ELQPPFNANHPLLLAADAVQYYQFLLAGLVPPGSPGPITRHGSYDSL 740
            ....||.|.|.|....: |:.||...::.|:.                        .||.   ||
  Fly   718 EVEARAQWNLGRRKDGSQEIAPPLGLDNWLIK------------------------DRHA---SL 755

Human   741 ASDHSGQED------EEWLSQVEIVTHTGPHRRLWMGPQFQFKTIH-PSG-----------QTTV 787
            ..|.:.|.|      |.||:||||:||.||||||||||||.||..: |||           :..|
  Fly   756 LLDSANQFDDPDERTESWLAQVEIITHAGPHRRLWMGPQFVFKNYNTPSGSNLNHVDAEAVEIGV 820

Human   788 ISSSSSVLQSHGPSDTPQPLLDFDTDDLDLNSLRIQPVRSDPVSMP------------GSSRPVS 840
            ..::::.|.|...|..           |.|.:: |...||.|::||            ||| .|:
  Fly   821 SKTTTTTLPSTAASSA-----------LGLGTI-IGKDRSSPLNMPLSAATSVGGAGIGSS-AVT 872

Human   841 DRRGVSTVIDAASGTF---DRSVTLLEVCGSWPEGFGLRHM-SSMEHTEEGLRERLADAMAESPS 901
            .|.|....:...||::   ::|..|:       :.|...|: |...|.:..|:|.|||||.||||
  Fly   873 GRSGAGVPVLIESGSYSSIEQSPKLM-------DRFRHGHLDSDYGHGDTRLKEDLADAMRESPS 930

Human   902 -----RDVVGS---------GTELQREGSIETLSNSSGSTSGSIPRNFDG--YRSPLPTNES 947
                 |:...:         |..|....|..:....:....||...|.|.  |...|..:||
  Fly   931 TAAARRETTAASVDQAAPPCGDHLATGASPASADLLAAGAGGSASSNCDNVCYYDALAEHES 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BCAS3	NP_001340073.1	BCAS3	611..783	CDD:463605	63/182 (35%)
rudhira	NP_001368979.1	BCAS3	635..818	CDD:463605	68/209 (33%)