Protein Alignment BCAS3 and F56C9.10

DIOPT Version :10

• Sequence 1: NP_001340073.1
• Gene: BCAS3 / 54828
• HGNCID: 14347
• Length: 958
• Species: Homo sapiens
• Sequence 2: NP_001360482.1
• Gene: F56C9.10 / 176040
• WormBaseID: WBGene00018953
• Length: 1035
• Species: Caenorhabditis elegans
• Alignment Length: 1012
• Identity: 251/1012 - (24%)
• Similarity: 414/1012 - (40%)
• Gaps: 242/1012 - (23%)

Human     1 MNEAMATDSPRRPS-RCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYS-----GTPLTEEKEK 59
            ||..|.  .||..| ....|.|||..||.:|:....||    |:|....|     .:.:|.||.:
 Worm   173 MNTIMT--KPRTNSVSYIKGQVVRQSAVEQQTLANQVV----DLVAMGMSKGQTQSSQITAEKAE 231

Human    60 IVWVRFENAD-LNDTSRNLEFHEIHSTGNEPPLLIMIGYSDGMQVWSIPI----SGEAQELFSVR 119
              ||:..:.: ..:.:..||             ::::|...|.|:|::.:    |||.:|:.|.|
 Worm   232 --WVQLTSVEKAGEPNERLE-------------VLIVGLCRGYQIWTMSMEFQQSGEFEEVLSER 281

Human   120 HGPIRAARILPAPQFGAQKCDNFAEKRPLLGVCKSIGSSGTSP--PYCCVDLYSLRTGEMVKSIQ 182
            .||:||.::||.......|.|:||:.|||:.:   :.:|...|  .||.|.:.||.||..|..|:
 Worm   282 QGPVRALKVLPNNLKLRGKKDSFADSRPLIAM---VDASSHHPDRQYCSVTIISLLTGREVHKIK 343

Human   183 FKTPIYDLHCNKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNP-IALGSRWLAYAENK 246
            |:.|:..::.:.:.|||.|.....|:|..||.:...:.:...|  .|..| ::|..:.||||:..
 Worm   344 FEEPVCAVNVSDQFLVVSLANMAYAYDILTFNEVRTIRTAPSC--ENSPPALSLSCQLLAYADTS 406

Human   247 LIRCHQSRGGACGD----NIQSYTATVISAAKTLKSGLTMVGKVVTQLTGTLPSGVTEDDVAIHS 307
            |....||.||...:    :.:.||..:.:|.......:    |.:::..|           |...
 Worm   407 LDLNLQSSGGLAAEVEATSSEKYTDHIYTAMSYFSRSV----KTISESVG-----------AGSG 456

Human   308 NSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTL 372
            :|.::....|:|||::        :.||.:.:|||::.|:.||..|:..:||:....|:::.|..
 Worm   457 SSTKANQPQGVITVLN--------LAVSGEDESDGVMCHYVAHVDPISYIAFSPDQRLVLSADAN 513

Human   373 GHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPY 437
            .:.|::|.::.|..|||..||.|||.|:||.|.|||....||.||||:.::|...|:|||.:.|:
 Worm   514 ANVFNIFLLMPHATSSSLAAVQHLYKLNRGSTPAKVVSTAFSEDCRWLAITTNHATTHVFAVCPF 578

Human   438 GGQPCVRTHMSPRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHANQQINT 502
            ||:|..||| ....||:.|||.:||||.: ..::|:..|            ||.....|:....|
 Worm   579 GGKPNQRTH-GDTFVNKESRFHRSAGLTD-AADVTASIG------------PSKHRAMADSCSYT 629

Human   503 KELIGSFLNVGRAYRLIGISGLSGKLNSQDSYNNFTNNNP------GNPRLSPLPSLMVVMPLAQ 561
            ||                              :....|:|      ||.|:.|.|..::::...:
 Worm   630 KE------------------------------HPIAVNSPTLAKTNGNSRVGPFPPPLLLVATEK 664

Human   562 IKQPMTLGTITKR-TGPYLFGAGCFSIKAPCKVKPPPQISPSKSMGG----EFCVAAIFGTSRSW 621
            ||.    ...||. ...:......||.       |..|.|.|.::..    |....::....:|:
 Worm   665 IKD----SRYTKEDLSAWAADMTSFSY-------PAAQASSSPAVAARRRLEVSRMSVMFRMKSY 718

Human   622 FANNAGLKREKDQSKQVVVESLYIIS---CYGTLV-EHMME------PRPLSTAPKISDDTPLEM 676
              |:....:....:|.::..||.|..   ..|.:| :|.::      ...:..:|:||
 Worm   719 --NSTTSTKTAKTTKMLMSMSLVIAKVDPAQGVIVTQHDIKSLRKEGETNMEASPQIS------- 774

Human   677 MTSPRASWTLVRTPQWNELQPPFNANHPLLLAADAVQYYQFLLAGLVPPGSPGPITRHGSYDSLA 741
             .:|...|.|.||....::..|..:..||:..|                          :.:::.
 Worm   775 -VAPVGGWILQRTKNNADMHAPMPSASPLMAFA--------------------------TVETVP 812

Human   742 SDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSHGPSDTPQP 806
            :...|.|| .|...||..|:..|||.:|.||||:........|.:::|..:   :....|....|
 Worm   813 AKRIGDED-VWTPHVETRTYLPPHRWIWQGPQFELFEYREDDQPSLMSPGN---KGSNASFKSIP 873

Human   807 LLDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGVSTVIDAASGTFDRSVTLLE-----VC 866
            :|                |.|:.|::...:.|..     :|.|:..|.|...|.::.:     |.
 Worm   874 VL----------------VGSEAVNITMKTIPAD-----ATRIECGSYTSANSYSIDQGSDQPVI 917

Human   867 GSWPEGFGLRHMSSMEHTEEGLRERLADAMAE-----------SPSRDVV-------GSGTELQR 913
            |.:.......:::|           :||||.:           ||..|.:       .|.|...|
 Worm   918 GGYSSATNGDYIAS-----------IADAMRDISSDDDSTKKKSPKNDDLIEEFFDTESSTPFAR 971

Human   914 EGSIETLSNSSGSTSGSI--PRNFDGYRSPLPTNESQ 948
            .||  ..|:|:|:|.|..  .:......:||||:.::
 Worm   972 NGS--GSSSSTGATGGKSLKKKKTPPASAPLPTSSTK 1006

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BCAS3	NP_001340073.1	BCAS3	611..783	CDD:463605	36/181 (20%)
F56C9.10	NP_001360482.1	None