DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DNAJB12 and CG11035

DIOPT Version :9

Sequence 1:	NP_001352009.1	Gene:	DNAJB12 / 54788	HGNCID:	14891	Length:	377	Species:	Homo sapiens
Sequence 2:	NP_001303469.1	Gene:	CG11035 / 40953	FlyBaseID:	FBgn0037544	Length:	231	Species:	Drosophila melanogaster

Alignment Length:	136	Identity:	40/136 - (29%)
Similarity:	64/136 - (47%)	Gaps:	16/136 - (11%)

- Green bases have known domain annotations that are detailed below.

Human   111 YYEILGVSRGASDEDLKKAYRRLALKFHPDKNH-APGATEAFKAIGTAYAVLSNPEKRKQYDQFG 174
            :|:.||:.|..:..::|.||.:|::.:|||:|. :..|.:.|:.|..||.:|.|...|:.||: |
  Fly    28 HYDALGIRRQCTQNEIKAAYYKLSMLYHPDRNQGSENAAKKFREINQAYEILGNYRLRRLYDK-G 91

Human   175 DDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGR---------MRYTYQ 230
            ...:..|::..   |.|...| .:..:|....|:...|..|.|. .|.||         .|..|.
  Fly    92 IVHTAGAQYAQ---DVHDVAE-PVVEDDAETKFYKSRFQKSRVS-DSAGRTPIYDFDEWSRNHYG 151

Human   231 QRQDRR 236
            :..|||
  Fly   152 KSFDRR 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB12	NP_001352009.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	45..92
		DnaJ	110..>236	CDD:333066	38/134 (28%)
		DUF1977	268..368	CDD:312722
CG11035	NP_001303469.1	DnaJ	26..>89	CDD:223560	20/60 (33%)
CG11035	NP_001303469.1	DnaJ	27..89	CDD:278647	20/60 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810