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Protein Alignment NSMCE4A and Nse4

DIOPT Version :10

Sequence 1:	NP_060085.2	Gene:	NSMCE4A / 54780	HGNCID:	25935	Length:	385	Species:	Homo sapiens
Sequence 2:	NP_609405.2	Gene:	Nse4 / 34434	FlyBaseID:	FBgn0032251	Length:	290	Species:	Drosophila melanogaster

Alignment Length:	321	Identity:	69/321 - (21%)
Similarity:	140/321 - (43%)	Gaps:	53/321 - (16%)

- Green bases have known domain annotations that are detailed below.

Human    68 MDPASLEAEADQGLCRQIRHQYRALINSVQQN---REDILN--AGDKLTEVLEEANTLFNEVSRA 127
            ||.:..:::.|....|.:|.|     |.:::|   .:.|.|  .|:.:| .:||.....|::|:.
  Fly     1 MDSSESQSQMDDQDARILRLQ-----NLIEKNIEIEQQIENNTIGESIT-AIEEIIQTANDISKG 59

Human   128 RE-AVLDAHFLVLASDLGKE------KAKQLRSDLSSFDMLRYVETLLTHMGVNPLEAEELIRDE 185
            .| ...::..|||.::|.:.      ||.|..::::.    |.|.|.:          .:|:..|
  Fly    60 HEDRRTNSTELVLDTELLRRNFEVVGKAIQHNTNVTD----RMVATAI----------NDLVFKE 110

Human   186 DSPDFEFIVYDSWKITGRTAENTFNKTHTFHFLLGSIYGECPVPKPRVDRPRKVPVIQEERAMPA 250
            ...|::.:.    .:..:.....|.......|:  .:..:..|.|.|..|..|..|.::......
  Fly   111 SEEDWDALC----SLAIQFGRPLFTNDSMLPFI--DVTPKVVVQKQRAPRKTKSQVDEKRPEKSD 169

Human   251 QLRRMEESHQEATE--KEVERILGLLQTYFREDPDTPMSFFDFVVDPHSFPRTVENIFHVSFIIR 313
            ||.|.:|.....|.  |::.:|       :|:....|:.:|..:.:|::|..||:|...:||:::
  Fly   170 QLERKDEGAASVTHMLKQIRQI-------YRDGNQEPIPYFKLICNPNNFMDTVQNALQLSFLVK 227

Human   314 DGFARIRLDQDRLPVIEPVSINEENEGFEHNTQVRNQGIIALSYRDWEEIVKTFEISEPVI 374
            :.:..|...:|.||::..|:    ::..|.|..  :|.|.::.....|::||.:.:.||::
  Fly   228 ENYISIENGEDGLPLVRVVN----SKSVEGNAP--SQAICSIDVTFCEKMVKHYNLHEPML 282

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.