Protein Alignment DIRAS2 and CG8641

DIOPT Version :10

• Sequence 1: NP_060064.2
• Gene: DIRAS2 / 54769
• HGNCID: 19323
• Length: 199
• Species: Homo sapiens
• Sequence 2: NP_648073.1
• Gene: CG8641 / 38771
• FlyBaseID: FBgn0035733
• Length: 434
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 75/235 - (31%)
• Similarity: 111/235 - (47%)
• Gaps: 37/235 - (15%)

Human     1 MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGS 65
            :|...|.||:.:.|:...||||:|.||:...|.|:|.||:|:.:|::......:..|.|.||:|.
  Fly   160 LPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGY 224

Human    66 HQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEI------------KGDVESIPIML 118
            |.||||:|||...|..||||:|:.||:|.||:..:.|.|.|.            |..:..||::|
  Fly   225 HPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMIL 289

Human   119 VGNKCDESPSREVQSSEAEA--LARTWKCAFMETSAKLNHNVKELFQELLNLEK----------R 171
            .|||||.. .:.||..|...  ..:...|.|:|.||:.|:.:.:||..|..:..          |
  Fly   290 AGNKCDRD-FKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHHR 353

Human   172 RTVSL------------QIDGKKSKQQKRKEKLKGKCVIM 199
            |.||:            .:.|.|......|.:....|.::
  Fly   354 RLVSVFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVV 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIRAS2	NP_060064.2	ARHI_like	7..170	CDD:206711	65/176 (37%)
		Effector region. /evidence=ECO:0000255	36..44		4/7 (57%)
CG8641	NP_648073.1	Rhes_like	167..434	CDD:133343	73/228 (32%)