DRSC/TRiP Functional Genomics Resources

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Protein Alignment LEPROT and CG30423

DIOPT Version :10

Sequence 1:NP_001185610.1 Gene:LEPROT / 54741 HGNCID:29477 Length:140 Species:Homo sapiens
Sequence 2:NP_726490.3 Gene:CG30423 / 246605 FlyBaseID:FBgn0050423 Length:126 Species:Drosophila melanogaster


Alignment Length:441 Identity:75/441 - (17%)
Similarity:123/441 - (27%) Gaps:168/441 - (38%)


- Green bases have known domain annotations that are detailed below.


Human     5 SFGDDMWLLTTLLLWVPVGGEVVNATKAVITLQPPWVSIFQKENVTLWCEGPHLPGDSS------ 63
            :.|||...:..|         |:::....|.||..:..|         |..|..|.|:.      
  Fly   146 TLGDDFPQMNRL---------VLDSNTCCILLQQRFPCI---------CPDPFDPMDAHLQNVLE 192

Human    64 --TQWFINGTAVQISTPSYSIPEASFQ---------------------------DSGEYRCQIGS 99
              .||||. ..:.:...|...||:..|                           :||..|..:..
  Fly   193 RIVQWFIK-DPIPLVRASNCTPESQQQELLEHAIAAQTKLMNEIAAMAEFWITLESGMLRPNLNL 256

Human   100 SMPSDPVQ------------------------LQIHNDWLLLQASRRVL---------------- 124
            |:.|.|..                        :.:.|:  .|:.|:|..                
  Fly   257 SIISQPANQNTTSAAAQPPPATTIGNVAKGQIVLVKNE--SLKPSKRFFRVGTTESIPWAYRKRD 319

Human   125 ---------TEGEPLALRCHGWKNKLV-------------YNVVFYRNGKSFQFSSDSEVAILKT 167
                     |.|||:      |:...:             |::|..|||......:|.:      
  Fly   320 PNGNILRNSTTGEPI------WEGYCIDFLHQLSVVMNFDYDLVSPRNGTFGLRDADGK------ 372

Human   168 NLSHSGIYHCSGTGRHRYTSAGVSIT---------VKELFTTPVLRASVSSPFPEGSLVTLNCET 223
               ..|:......|...:..|.:.:|         |...|....:..::..|..|.||...   .
  Fly   373 ---WDGLVGDLVVGEIDFAIASLKMTAEREEVVDFVAPYFEQTGILIAMRKPVRETSLFKF---M 431

Human   224 NLLLQRPGLQLHFSFYVGSKILEYRNTSSEYHIARAEREDAGFYWCEVATEDSSVLKRSPELELQ 288
            .:|.....|.:..:....:.:|...:..|.|  :....:||..|.|...|     ||.|....|.
  Fly   432 TVLRLEVWLSILLAIVATAVMLWLLDKFSPY--SAKNNKDAYPYECRKFT-----LKESFWFALT 489

Human   289 VLGPQSS-------------APVWFHILFYLSVGIMFSLNTVLYVKIHRLQ 326
            ...||..             |..|..::..|:.   |:.|...::.:.|:|
  Fly   490 SFTPQGGGEAPKALSGRTLVAAYWLFVVLMLAT---FTANLAAFLTVERMQ 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LEPROTNP_001185610.1 Vps55 16..133 CDD:461188 32/200 (16%)
CG30423NP_726490.3 Vps55 7..121 CDD:461188
Blue background indicates that the domain is not in the aligned region.

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