Protein Alignment FEV and Ets96B

DIOPT Version :10

• Sequence 1: NP_059991.1
• Gene: FEV / 54738
• HGNCID: 18562
• Length: 238
• Species: Homo sapiens
• Sequence 2: NP_996290.1
• Gene: Ets96B / 42952
• FlyBaseID: FBgn0039225
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 179
• Identity: 71/179 - (39%)
• Similarity: 93/179 - (51%)
• Gaps: 35/179 - (19%)

Human    39 AVQKGSGQIQLWQFLLELLAD-RANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLS 102
            |:.:..|.:||||||:.||.: ..:|.||||.|...||||.:|:|||||||.:|::|.|||||||
  Fly   490 AISQRRGSLQLWQFLVALLDEPTTSASCIAWTGRGMEFKLIEPEEVARRWGLQKNRPAMNYDKLS 554

Human   103 RALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQPPP----AHAHAAAAAAAAAAAAQDGALYKL 163
            |:|||||:|.||.||:|:||.|||       .|.|..    |:.|....:.       .|..::|
  Fly   555 RSLRYYYEKGIMQKVNGERYVYRF-------VCDPDALFNMAYGHLTTGSG-------KGDQHQL 605

Human   164 PAGLAPLPFPGLSKLNLMAASAGVAPAGFSYWPGPGPAATAAAATAALY 212
            ...||..|                ..:|.|....|..|.:....||||:
  Fly   606 TLSLAKTP----------------PTSGDSQTQSPRVAKSEYYDTAALH 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FEV	NP_059991.1	ETS	46..131	CDD:197710	52/85 (61%)
		May mediate active transcriptional repression	129..238		17/88 (19%)
Ets96B	NP_996290.1	ETS	497..583	CDD:197710	53/92 (58%)