DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FEV and Ets21C

DIOPT Version :10

Sequence 1:NP_059991.1 Gene:FEV / 54738 HGNCID:18562 Length:238 Species:Homo sapiens
Sequence 2:NP_523445.1 Gene:Ets21C / 33229 FlyBaseID:FBgn0005660 Length:475 Species:Drosophila melanogaster


Alignment Length:235 Identity:103/235 - (43%)
Similarity:117/235 - (49%) Gaps:77/235 - (32%)


- Green bases have known domain annotations that are detailed below.


Human    40 VQKGS-GQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSR 103
            |.:|| |||||||||||||||.:||..|:|||..|||:|.|||||||||||||:|||||||||||
  Fly   247 VAQGSGGQIQLWQFLLELLADSSNANAISWEGQSGEFRLIDPDEVARRWGERKAKPNMNYDKLSR 311

Human   104 ALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQ-----------------------------PPP 139
            |||||||||||:|||||||||:|||.||..|||                             |||
  Fly   312 ALRYYYDKNIMTKVHGKRYAYKFDFHGLMAACQAQAQGGDPASSMLGSYNHHAGGAMQLGRHPPP 376

Human   140 AHAH---------------------------------AAAAAAAAAAAAQDGALYKLPAGLAPLP 171
            .|.|                                 :::.|::.|:..|..|...........|
  Fly   377 LHHHPQHSHPHHQLGQPHFLHPHHSSPASNSSSLGFPSSSTASSQASPGQAPASSSASTSNFTAP 441

Human   172 FPGLSKLNLMAASAGVAPAGFS------YWPGPGPAATAA 205
            |.|        .:|||.||..|      |..||....|.|
  Fly   442 FQG--------GTAGVDPARTSTSSAGNYDQGPVTPTTNA 473

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FEVNP_059991.1 ETS 46..131 CDD:197710 71/84 (85%)
May mediate active transcriptional repression 129..238 28/145 (19%)
Ets21CNP_523445.1 SAM_PNT 149..217 CDD:188876
ETS 254..339 CDD:197710 71/84 (85%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.