Protein Alignment RAB39A and Rab11

DIOPT Version :10

• Sequence 1: NP_059986.1
• Gene: RAB39A / 54734
• HGNCID: 16521
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Alignment Length: 215
• Identity: 92/215 - (42%)
• Similarity: 135/215 - (62%)
• Gaps: 18/215 - (8%)

Human     7 YQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAG 71
            |.|::::||||.||||.||.|||:..| .|.|.:   |:||:|.:|.:|:: ||.||.|:|||||
  Fly    10 YLFKVVLIGDSGVGKSNLLSRFTRNEF-NLESKS---TIGVEFATRSIEVD-GKTIKAQIWDTAG 69

Human    72 QERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMYVQPFRIVFLLVGHKCDLASQRQ 136
            |||:|:||.:|||.:||..||:||....::|:|:.||.|.:.:... .||.:|||:|.||...|.
  Fly    70 QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQ-NIVIMLVGNKSDLRHLRS 133

Human   137 VTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNT 201
            |..:||:..:...|:.:|||||.|:||||.:|..:..:||.::.:.:  |:|..||  ....|:.
  Fly   134 VPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQ--IRDPPEG--DVIRPSN 194

Human   202 VHSSEEAVKP------RKEC 215
            |...:  |||      ||:|
  Fly   195 VEPID--VKPTVTADVRKQC 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39A	NP_059986.1	Rab39	7..217	CDD:133311	92/215 (43%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		10/15 (67%)
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	78/168 (46%)