Protein Alignment RAB39A and Rab8

DIOPT Version :10

• Sequence 1: NP_059986.1
• Gene: RAB39A / 54734
• HGNCID: 16521
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 179
• Identity: 82/179 - (45%)
• Similarity: 124/179 - (69%)
• Gaps: 14/179 - (7%)

Human     1 METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQ 65
            |...:.|.|:|::||||.|||:|:|.||::..|    :.....|:|:||..|.:|:: .|:||||
  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAF----NTTFISTIGIDFKIRTIELD-NKKIKLQ 60

Human    66 LWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWL----EEAKMYVQPFRIVFLLVG 126
            :||||||||||:||.:|||.::|..||:|||..:|||::|:|:    |.|...|:.     :|:|
  Fly    61 IWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEK-----MLLG 120

Human   127 HKCDLASQRQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDI 175
            :||:|..:|||::|..|:|:.:.|:|::|||||.:.||||:|..|..||
  Fly   121 NKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDI 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39A	NP_059986.1	Rab39	7..217	CDD:133311	81/173 (47%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		11/15 (73%)
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/174 (47%)