Protein Alignment RAB39A and Rab14

DIOPT Version :10

• Sequence 1: NP_059986.1
• Gene: RAB39A / 54734
• HGNCID: 16521
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_788056.1
• Gene: Rab14 / 34840
• FlyBaseID: FBgn0015791
• Length: 239
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 90/212 - (42%)
• Similarity: 136/212 - (64%)
• Gaps: 7/212 - (3%)

Human     7 YQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAG 71
            |.|:.|:|||..||||||||:||:.:|    ...|..|:||:|.:|::|:: .|:||||:|||||
  Fly    34 YIFKYIIIGDMGVGKSCLLHQFTEKKF----MANCPHTIGVEFGTRIIEVD-DKKIKLQIWDTAG 93

Human    72 QERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMYVQPFRIVFLLVGHKCDLASQRQ 136
            |||||::||||||.:.|..:|:|||.|.::.|:..||.:.:....|..::| |:|:|.||.|.|:
  Fly    94 QERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDTRNLTNPSTVIF-LIGNKSDLESTRE 157

Human   137 VTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVK-SGFVPN 200
            ||.|||::.:.:.|:.::|.||....||||:|....|.||:.|::|.:.:.....||: ....|:
  Fly   158 VTYEEAKEFADENGLMFLEASAMTGQNVEEAFLETARKIYQNIQEGRLDLNASESGVQHRPSQPS 222

Human   201 TVHSSEEAVKPRKECFC 217
            ....|.||...:.:|.|
  Fly   223 RTSLSSEATGAKDQCSC 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39A	NP_059986.1	Rab39	7..217	CDD:133311	89/210 (42%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		12/15 (80%)
Rab14	NP_788056.1	Rab14	34..199	CDD:133322	80/170 (47%)