Protein Alignment RAB39A and Rab10

DIOPT Version :10

• Sequence 1: NP_059986.1
• Gene: RAB39A / 54734
• HGNCID: 16521
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 173
• Identity: 74/173 - (42%)
• Similarity: 113/173 - (65%)
• Gaps: 14/173 - (8%)

Human     9 FRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQE 73
            |:|::||||.|||:|:|.||:...|    :.....|:|:||..:.:|:. ||:||||:|||||||
  Fly    10 FKLLLIGDSGVGKTCILFRFSDDAF----TSTFISTIGIDFKIKTVELR-GKKIKLQIWDTAGQE 69

Human    74 RFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWL----EEAKMYVQPFRIVFLLVGHKCDLASQ 134
            ||.:||.||||.::|..||:||||.:|||::..||    |.|...|:.     :::|:|||:..:
  Fly    70 RFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEK-----MILGNKCDMTDK 129

Human   135 RQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYE 177
            |.|.:|..|.::.:.|::::|||||...|:|.:|..|...|.:
  Fly   130 RVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILD 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39A	NP_059986.1	Rab39	7..217	CDD:133311	74/173 (43%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		11/15 (73%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	74/173 (43%)