Protein Alignment RAB39A and CG4789

DIOPT Version :10

• Sequence 1: NP_059986.1
• Gene: RAB39A / 54734
• HGNCID: 16521
• Length: 217
• Species: Homo sapiens
• Sequence 2: NP_573166.1
• Gene: CG4789 / 32668
• FlyBaseID: FBgn0030792
• Length: 274
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 47/212 - (22%)
• Similarity: 81/212 - (38%)
• Gaps: 59/212 - (27%)

Human    10 RLIVIGDSTVGKSCLLHRFTQGRF---PGLRSPACDPTVGVDFFSRLLEIEPGKRIK----LQLW 67
            |::|:|||.|||:.|.|..|....   ||.       |||.:...::.....|...:    ::|:
  Fly     8 RIVVVGDSGVGKTSLTHLITHNEALIRPGW-------TVGCNIQVKMHPFREGTARECPYFVELF 65

Human    68 DTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEE--------------AKMYVQP- 117
            |..|....::....:|....|..||.|:||.:|...:.|||.|              |.|...|
  Fly    66 DVGGSLNHKNTRSVFYAGIDGIILVHDLTNAKSQRQLIDWLYEIVNKEGKDTNKSNGASMPPSPP 130

Human   118 --------------FRIVF-------------LLVGHKCDLASQRQVTREEAEK---LSADCGMK 152
                          ..|:|             |::|.|.||..:::..:...:|   ::..||.:
  Fly   131 SPLSSFSTDNLGTDGHILFDMEEFLGATQTPILVMGTKLDLLDEKRHPKMGVKKPGGIADKCGAE 195

Human   153 YIETSAKDATNVEESFT 169
            .|..:.:::.::....|
  Fly   196 EIWLNCRNSRSLAAGTT 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB39A	NP_059986.1	Rab39	7..217	CDD:133311	47/212 (22%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	39..47		2/7 (29%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	71..87		2/15 (13%)
CG4789	NP_573166.1	P-loop containing Nucleoside Triphosphate Hydrolases	7..228	CDD:476819	47/212 (22%)