Protein Alignment RBFOX1 and Rbfox1

DIOPT Version :10

• Sequence 1: XP_016878807.1
• Gene: RBFOX1 / 54715
• HGNCID: 18222
• Length: 623
• Species: Homo sapiens
• Sequence 2: XP_038941737.1
• Gene: Rbfox1 / 302920
• RGDID: 1311210
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 499/587 - (85%)
• Similarity: 513/587 - (87%)
• Gaps: 31/587 - (5%)

Human    41 MASPSGSSEATGKPR-GRDGRPRREEDDVPPEEKRLRLGLEGGSAQPEDCEDGKDAPRPG---RE 101
            ||||.||.|...|.| .|:||.|||:|  .||:|||||||..|| :|   :||...|||.   |:
  Rat     1 MASPPGSPEDADKLRESREGRQRREDD--APEQKRLRLGLRAGS-EP---QDGATTPRPARDERD 59

Human   102 ETGTQTGGDGRGDLLCLPYSLVEGQDYKSENSTLLPGAKNSLQDSVSASQATGKAEETGQRTHAS 166
            |..|||||:||.:.|.||.||||.|                    |..|....:||||.||.|.|
  Rat    60 ELATQTGGEGRSEQLSLPPSLVESQ--------------------VLVSPPVDQAEETAQRPHES 104

Human   167 GTYSFLDRTQHSDIKADCNTCVEIEDRKVSRQQMNCEREQLRGNQEAAAAPDTMAQPYASAQFAP 231
            |||.|||:.|||||||||:.|||.|||||.||.||||||||||||||||||||||||||||||||
  Rat   105 GTYGFLDQAQHSDIKADCSNCVETEDRKVLRQPMNCEREQLRGNQEAAAAPDTMAQPYASAQFAP 169

Human   232 PQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAP 296
            |||||||||||||||||||||||||||:||||||||.||||||| ||||||||||||||||||||
  Rat   170 PQNGIPAEYTAPHPHPAPEYTGQTTVPDHTLNLYPPTQTHSEQS-ADTSAQTVSGTATQTDDAAP 233

Human   297 TDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVT 361
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   234 TDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVT 298

Human   362 FENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGT 426
            ||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||:|||||
  Rat   299 FENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKAVNPYTNGWKLNPVVGAVYSPDFYAGT 363

Human   427 VLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPI 491
            |||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   364 VLLCQANQEGSSMYSGPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPI 428

Human   492 PAYGGVVYQEPVYGNKLLQGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFML 556
            ||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||
  Rat   429 PAYGGVVYQEPVYGNKLLQGGYAAYRYAQPTPATAAAYSDRNQFVFVATDEISCNTSAVTDEFML 493

Human   557 PTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQAAENLTASPPLLQFMFKVIVAQE 621
            ||||||||||||||||||||||||||||||||||.||||||||||:|.|||||||||||||||||
  Rat   494 PTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCRLPGLCCQAAEHLPASPPLLQFMFKVIVAQE 558

Human   622 RK 623
            ||
  Rat   559 RK 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBFOX1	XP_016878807.1	PRK12323	<212..346	CDD:481241	130/133 (98%)
		RRM_FOX1_like	316..391	CDD:409841	74/74 (100%)
		Fox-1_C	452..543	CDD:463568	89/90 (99%)
Rbfox1	XP_038941737.1	ELAV_HUD_SF	<123..324	CDD:273741	193/201 (96%)
		RRM_FOX1_like	253..328	CDD:409841	74/74 (100%)
		Fox-1_C	389..480	CDD:463568	89/90 (99%)