Protein Alignment PDP1 and Nil

DIOPT Version :10

• Sequence 1: XP_016869077.1
• Gene: PDP1 / 54704
• HGNCID: 9279
• Length: 591
• Species: Homo sapiens
• Sequence 2: NP_651472.2
• Gene: Nil / 43185
• FlyBaseID: FBgn0039421
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 80/333 - (24%)
• Similarity: 115/333 - (34%)
• Gaps: 121/333 - (36%)

Human   160 VSSILGFDSNQLPANAPIEDRRSAATCLQ---TRGMLLGVFDGHAGCACSQAVSERLFYYIAVSL 221
            |||:.|:       ...:||..|||..|:   .......|||||||...|...:|.|.
  Fly    30 VSSMQGW-------RLEMEDSHSAACRLKDPFATWSYFAVFDGHAGSQISLHCAEHLM------- 80

Human   222 LPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLRTYWQELIDLNTGESTDIDV 286
               .|:||.|:                     |||..   |...:|
  Fly    81 ---STILESES---------------------FSKHK---YEAGIR------------------- 99

Human   287 KEALINAFKRLDNDIS--LEAQVGDPNSFLNYLVLRVAFSGATACVAHVDGVDLHVANTGDSRAM 349
                 ..|.:||.|:.  ...|.|                |:||....|....:::.|.|||||:
  Fly   100 -----EGFLQLDEDMRKLYHDQQG----------------GSTAICVFVSPDKIYLVNCGDSRAV 143

Human   350 LGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKW 414
            :   ..:|  :||..:.||...:.:|.||::      .|...|...|:.|.|...|||||..||
  Fly   144 I---SRNG--AAVISTIDHKPFSPKEQERIQ------NAGGSVMIKRINGTLAVSRAFGDYDFK- 196

Human   415 SIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPPYLTAEPEVTYHRLRPQDKFLVLATDGLWETMH 479
                            ||...:   |.:....|    ||::........|:|:|:|.||:|:.|.
  Fly   197 ----------------NDGSKS---PVDQMVSP----EPDIIVCNRSEHDEFIVVACDGIWDVMT 238

Human   480 RQDVVRIV 487
            ..:|...:
  Fly   239 SSEVCEFI 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDP1	XP_016869077.1	PP2Cc	163..579	CDD:238083	77/330 (23%)
Nil	NP_651472.2	PP2Cc	27..277	CDD:238083	80/333 (24%)
		PP2C_C	284..355	CDD:429684