Protein Alignment GTPBP2 and gtpbp2

DIOPT Version :10

• Sequence 1: NP_061969.3
• Gene: GTPBP2 / 54676
• HGNCID: 4670
• Length: 602
• Species: Homo sapiens
• Sequence 2: NP_001072714.1
• Gene: gtpbp2 / 780171
• XenbaseID: XB-GENE-996416
• Length: 584
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 493/592 - (83%)
• Similarity: 532/592 - (89%)
• Gaps: 16/592 - (2%)

Human     1 MDSRVSELFGGCCRPGGGPAVGGTLKARGAGSSSGCGGPKGKKK-NGRNRGGKANNPPYLPPEAE 64
            |:.||.||||    |.|           |:|.:...|..||||. .||.|..|:|||||||||||
 Frog     1 MEPRVFELFG----PAG-----------GSGGTGARGKTKGKKAGKGRGRSSKSNNPPYLPPEAE 50

Human    65 DGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHR 129
            :||||||||||||||||||||||||||||||||||||||||||||||||||:||||:|||.||||
 Frog    51 EGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLSEEEMKASLHTLHR 115

Human   130 MAEKVGADITVLREREVDYDSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQ 194
            ||||||||||||||||||||||.||||||||:|||||||||||||||||||||||||||||||||
 Frog   116 MAEKVGADITVLREREVDYDSDSPRKITEVLIRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQ 180

Human   195 GELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFI 259
            ||||||||||||||||||||||||||||||||||||||||||:|||:|||||:||||:|||||||
 Frog   181 GELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVINYSESRTAEQICESASKMITFI 245

Human   260 DLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKIDLCAKT 324
            |||||||||.||||||||||||.|:|:||||||||||||||||||:|||||||:||||:||||..
 Frog   246 DLAGHHKYLKTTIFGLTSYCPDFAMLVVSANTGIAGTTREHLGLAMALKVPFFLVVSKVDLCAAA 310

Human   325 TVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFL 389
            |||||:|||||.||||||:|||.:|.|||||||||||||||||:||||.:|||:|||||||||||
 Frog   311 TVERTLRQLERTLKQPGCNKVPFMVRSEDDAVTAAQQFAQSPNITPIFAISSVTGESLDLLKVFL 375

Human   390 NILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLEL 454
            |||||||||.|||||||||.|||||||||||||||||||||.||:|:||:.|||||||.|.||.|
 Frog   376 NILPPLTNSHEQEELMQQLPEFQVDEIYTVPEVGTVVGGTLYSGVCKEGEHLVVGPTDGGGFLPL 440

Human   455 RVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTF 519
            :|||||||||.|||||||||||||||:|:|:|||||||:||||..||:|.|||||||||||||:.
 Frog   441 KVCSIQRNRSTCRVLRAGQAATLALGEFERSLLRKGMVLVSPEALPTVCWVFEAEIVLLFHATSC 505

Human   520 RRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGH 584
            |:|.||||||||||||||:|.||.||:|||||||||||||:|||||||.|.|||||||:||||||
 Frog   506 RQGVQVTVHVGNVRQTAVLEHIHGKDELRTGEKAVVRFRFIKHPEYLKPGTKLLFREGMTKGIGH 570

Human   585 VTDVQAI 591
            |..:|.|
 Frog   571 VCSLQVI 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTPBP2	NP_061969.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..64		21/48 (44%)
		GTPBP1_like	174..394	CDD:206728	196/219 (89%)
		GTPBP_II	409..495	CDD:293895	70/85 (82%)
		GTPBP_III	501..588	CDD:294007	71/86 (83%)
gtpbp2	NP_001072714.1	GTPBP1_like	160..380	CDD:206728	196/219 (89%)
		GTPBP_II	395..481	CDD:293895	70/85 (82%)
		GTPBP_III	487..574	CDD:294007	71/86 (83%)