Protein Alignment GTPBP2 and gtpbp2b

DIOPT Version :10

• Sequence 1: NP_061969.3
• Gene: GTPBP2 / 54676
• HGNCID: 4670
• Length: 602
• Species: Homo sapiens
• Sequence 2: NP_001338603.1
• Gene: gtpbp2b / 570143
• ZFINID: ZDB-GENE-050208-373
• Length: 605
• Species: Danio rerio
• Alignment Length: 568
• Identity: 475/568 - (83%)
• Similarity: 516/568 - (90%)
• Gaps: 11/568 - (1%)

Human    26 KARGAGSSSGCGGPKGK------KKNGRNRGGKANN-PPYLPPEAEDGNIEYKLKLVNPSQYRFE 83
            ||..:|:.:   .||.|      |:..|.||.|||. ||:||||||:||||||||||||:|||||
Zfish    22 KAAESGTET---APKKKSRTRRGKRGKRRRGKKANEPPPFLPPEAEEGNIEYKLKLVNPTQYRFE 83

Human    84 HLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRASLKTLHRMAEKVGADITVLREREVDY 148
            ||.||:||||||||||||||||||||||||||.||:|:||||||.|||||||||||:|||||||.
Zfish    84 HLATQLKWRLQEGRGEAVYQIGVEDNGLLVGLTEEDMKASLKTLRRMAEKVGADITLLREREVDC 148

Human   149 DSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLH 213
            |. ..|||.|||||||||:||||||||||||||||||||||||||||||||||||||||||||||
Zfish   149 DR-ARRKIAEVLVRKVPDDQQFLDLRVAVLGNVDSGKSTLLGVLTQGELDNGRGRARLNLFRHLH 212

Human   214 EIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHHKYLHTTIFGLTSY 278
            |||:|||||||||||||||||||||||||||||||||||||||||||||||:|||.|||||||||
Zfish   213 EIQTGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESSSKMITFIDLAGHYKYLKTTIFGLTSY 277

Human   279 CPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSKIDLCAKTTVERTVRQLERVLKQPGCH 343
            |||.|:|:|.||||||||||||||||:|||||.||||||:|||.|:|||:||||||||||||||:
Zfish   278 CPDFAMLVVGANTGIAGTTREHLGLAMALKVPIFIVVSKVDLCGKSTVEKTVRQLERVLKQPGCN 342

Human   344 KVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESLDLLKVFLNILPPLTNSKEQEELMQQL 408
            |:||:|.:.|||||||||||||.:|||||||||||||:|||||||.||||||:||||||||||||
Zfish   343 KIPMVVANPDDAVTAAQQFAQSSSVTPIFTLSSVSGENLDLLKVFFNILPPLSNSKEQEELMQQL 407

Human   409 TEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTDDGCFLELRVCSIQRNRSACRVLRAGQ 473
            |||||||||:||:|||||||||.||:|||||:|||||||||.||.|:||||.||||.||||||||
Zfish   408 TEFQVDEIYSVPDVGTVVGGTLYSGVCREGDRLVVGPTDDGKFLRLKVCSIHRNRSGCRVLRAGQ 472

Human   474 AATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVLLFHATTFRRGFQVTVHVGNVRQTAVV 538
            |||||||:|||:|||||||||||:||||||..|||.|||||||.|||||||||||:|||||||.|
Zfish   473 AATLALGNFDRSLLRKGMVMVSPKMNPTICWQFEAAIVLLFHAKTFRRGFQVTVHIGNVRQTATV 537

Human   539 EKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFREGVTKGIGHVT 586
            |.:..|::|||||:|||.||||||||||:|||||||||||||||||||
Zfish   538 ECLLGKEELRTGERAVVCFRFLKHPEYLRVGAKLLFREGVTKGIGHVT 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTPBP2	NP_061969.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..64		19/44 (43%)
		GTPBP1_like	174..394	CDD:206728	196/219 (89%)
		GTPBP_II	409..495	CDD:293895	73/85 (86%)
		GTPBP_III	501..588	CDD:294007	71/86 (83%)
gtpbp2b	NP_001338603.1	GTPBP1_like	173..393	CDD:206728	196/219 (89%)
		GTPBP_II	408..494	CDD:293895	73/85 (86%)
		GTPBP_III	500..587	CDD:294007	71/86 (83%)