Protein Alignment GTPBP2 and slfl-5

DIOPT Version :10

• Sequence 1: NP_061969.3
• Gene: GTPBP2 / 54676
• HGNCID: 4670
• Length: 602
• Species: Homo sapiens
• Sequence 2: NP_506069.1
• Gene: slfl-5 / 179677
• WormBaseID: WBGene00011449
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 238/532 - (44%)
• Similarity: 356/532 - (66%)
• Gaps: 4/532 - (0%)

Human    59 LPPEAEDGNIEYKLKLVNPSQYRFEHLVTQMKWRLQEGRGEAVYQIGVEDNGLLVGLAEEEMRAS 123
            ||||.|.||||||.|||||:..|.:||:|||||||:||:|||:|:|||||.|::.||.:||:..|
 Worm    54 LPPETELGNIEYKAKLVNPTTSRIQHLITQMKWRLREGQGEAIYEIGVEDGGIMSGLTDEELNDS 118

Human   124 LKTLHRMAEKVGADITVLREREVDY-DSDMPRKITEVLVRKVPDNQQFLDLRVAVLGNVDSGKST 187
            |:||..||:.:||.:.:|.|::|.. .|:..|.:.||||||||::|||:::|:||:|..|.||||
 Worm   119 LRTLRTMAQALGASMVILTEKDVTVKGSNSRRTVVEVLVRKVPESQQFIEVRLAVVGGCDVGKST 183

Human   188 LLGVLTQGELDNGRGRARLNLFRHLHEIQSGRTSSISFEILGFNSKGEVVNYSDSRTAEEICESS 252
            |.||||||.||:|.|:||:.:||..||:::|:|||:..:::||:::|::|||:.: :.||:.|.|
 Worm   184 LCGVLTQGCLDDGNGKARIGIFRFPHEVRTGKTSSVCNDVIGFDNRGKLVNYAQN-SLEEMVEKS 247

Human   253 SKMITFIDLAGHHKYLHTTIFGLTSYCPDCALLLVSANTGIAGTTREHLGLALALKVPFFIVVSK 317
            ||::|.|||||..||..|||.|||.|.|..|.|:|:|:.||...|||||||..||.:|.|::::|
 Worm   248 SKLVTLIDLAGDAKYQKTTIHGLTGYTPHFACLVVAADRGITWATREHLGLIAALNIPMFVLITK 312

Human   318 IDLCAKTTVERTVRQLERVLKQPGCHKVPMLVTSEDDAVTAAQQFAQSPNVTPIFTLSSVSGESL 382
            :||..:..:::.::.:..::.:.|.......|.::.|||.|||:.... ::.|:..:||||||..
 Worm   313 MDLVDRQGLKKIIKDVSNLVAKAGMTAREKRVKTKRDAVKAAQELCVG-SIVPVLAVSSVSGEGF 376

Human   383 DLLKVFLNILPPLTNSKEQEELMQQLTEFQVDEIYTVPEVGTVVGGTLSSGICREGDQLVVGPTD 447
            ..|:..||.|.....::.:.:|:.....|.::|:|.||.||.||||.||.|...||..::|||..
 Worm   377 RCLRTLLNCLSTAGTAESRIQLVGLPAFFTIEELYNVPHVGQVVGGMLSEGQLHEGADVLVGPMK 441

Human   448 DGCFLELRVCSIQRNRSACRVLRAGQAATLALGDFDRALLRKGMVMVSPEMNPTICSVFEAEIVL 512
            ||.|.::.|.||:|:|.|...:..|:||:::|...|...||:|||:...:..|.:|..|.|.::|
 Worm   442 DGTFEKITVGSIRRSRQAVGCVNPGEAASISLNLPDGVSLRRGMVLAEIDHQPPVCYEFTANLLL 506

Human   513 LFHATTF-RRGFQVTVHVGNVRQTAVVEKIHAKDKLRTGEKAVVRFRFLKHPEYLKVGAKLLFRE 576
            |.|:|.: ..|||.||.:|:|..||::..|...|.:|.|:.|||:..|...||.::.|:.::.|:
 Worm   507 LCHSTKYICEGFQATVFIGSVCTTAIITHIDDADCIRPGKWAVVKMCFAYQPEVIREGSPIILRQ 571

Human   577 GVTKGIGHVTDV 588
            |.|||:|.|..|
 Worm   572 GKTKGMGEVLKV 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GTPBP2	NP_061969.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..64		4/4 (100%)
		GTPBP1_like	174..394	CDD:206728	97/219 (44%)
		GTPBP_II	409..495	CDD:293895	38/85 (45%)
		GTPBP_III	501..588	CDD:294007	34/87 (39%)
slfl-5	NP_506069.1	GTPBP1_like	170..389	CDD:206728	97/220 (44%)
		GTPBP_II	403..489	CDD:293895	38/85 (45%)
		GTPBP_III	496..583	CDD:294007	34/86 (40%)