Protein Alignment POU6F1 and nub

DIOPT Version :9

• Sequence 1: XP_016874997.1
• Gene: POU6F1 / 5463
• HGNCID: 9224
• Length: 613
• Species: Homo sapiens
• Sequence 2: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 143/539 - (26%)
• Similarity: 213/539 - (39%)
• Gaps: 140/539 - (25%)

Human   100 SQAPSQPQASQTLTPLAVQAAPQVLTQENLATVLTGVMVPAGAVTQPLLIPISIAGQVAGQQGLA 164
            :|:||....|.|.:|:.|.:.|.                |...:..|:|.|.....
  Fly   505 TQSPSNSVKSATASPVPVISVPS----------------PVPPMISPVLAPSGCGS--------- 544

Human   165 VWTIPTATVAALPGLTAASPTGGVFKPPLAGLQAAAVLNTALPAPVQAAAPVQASSTAQPRP--- 226
              |.|.:..||.....|.:.|.|....||          .|||......|.:.|:......|
  Fly   545 --TTPNSMAAAAAAAAAVASTMGSGISPL----------LALPGMSSPQAQLAAAGLGMNNPLLT 597

Human   227 -PAQPQTLFQTQPLLQTTPAILPQPTAATAAAPTPKPVDTPPQITVQPAGFAFSPGIISAASLG- 289
             ...||...|...|||.....|.|.                         |.....::.:.|||
  Fly   598 GSLSPQDFAQFHQLLQQRQVALTQQ-------------------------FNSYMELLRSGSLGL 637

Human   290 GQTQILGSLTTAPVITSAIPSMPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVT 354
            .|..        |.:|:.:     .::|.|..:|.|.:       :.||....|..:..|.|...
  Fly   638 AQDD--------PALTAQV-----AAAQFLMQSQLQAL-------SQASQQLQALQKQQQRQVDE 682

Human   355 PQLLLNAQGQVIATLASSPLPPPVAVRKP-STPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 418
            |..|.:...|...:.....:..|:|:|.| |:|:........|:|.||
  Fly   683 PLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITP----------------- 730

Human   419 PSASAPIPITCSETPT-------VSQLVSSLEPHT------------PSLDEDGINLEEIREFAK 464
            ||::|.:.::...||:       :||..::.:|.|            || .|:..:|||:.:|||
  Fly   731 PSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPS-PEETTDLEELEQFAK 794

Human   465 NFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQ 529
            .||.||:.||.||..||.|:....|..:||:.|.|||.|:::.|:..||||:|:|||::|:...|
  Fly   795 TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQ 859

Human   530 -----------EGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKEL 583
                       :...:..|.:|    ::||:|||.......||...|..|..||.:|||::|..|
  Fly   860 ATGGVFDPAALQATVSTPEIIG----RRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRL 920

Human   584 NYDREVVRVWFCNRRQTLK 602
            :.::||||||||||||..|
  Fly   921 SMEKEVVRVWFCNRRQKEK 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU6F1	XP_016874997.1	Atrophin-1	<41..407	CDD:331285	64/312 (21%)
		POU	451..525	CDD:197673	35/73 (48%)
		Homeobox	549..602	CDD:306543	26/52 (50%)
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	31/63 (49%)
		Homeobox	886..939	CDD:278475	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910