Protein Alignment CCNJ and CycE

DIOPT Version :10

• Sequence 1: XP_016871843.1
• Gene: CCNJ / 54619
• HGNCID: 23434
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 483
• Identity: 93/483 - (19%)
• Similarity: 172/483 - (35%)
• Gaps: 101/483 - (20%)

Human    10 VTPPGEGA---QRVAGEPAVTAPGVCLTD-------SSCRVGLGAPPGP--------MELEGQWW 56
            ::|...|.   |.|.||   ..||:....       |...:.:..|..|        ..|....|
  Fly   267 ISPASSGCSQQQAVNGE---RTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAW 328

Human    57 RGQLAADIHQALRYKE-----LKLPSYKGQSPQLS--LRRYFADLIAIVSNRFTLCPSARHLAVY 114
            ..  |||:.:.:.:::     |:..|...|.|.|.  :|....|.:..|...:.|.....:|||.
  Fly   329 AN--AADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVD 391

Human   115 LLDLFMD-RYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQ---LNSLGCMTNMNLVLTKQNL 175
            .||.::. .:.:....|.|:.::||.:|:|.||...  ||:.:   :....|        |::::
  Fly   392 YLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYP--PKIGEFAYVTDGAC--------TERDI 446

Human   176 LHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYF----- 235
            |:.|.:||:...|::...|...::..|:     :.::::..|....:..:...|:..|.|
  Fly   447 LNHEKILLQALDWDISPITITGWLGVYM-----QLNVNNRTPASFSQIGRQKSAEADDAFIYPQF 506

Human   236 -----------LEVSLQDYAFLNYAPSLVAAACVA---SSRIILRLSPTWPTRLHRLTAYSWDFL 286
                       |::...|....||:.|::|||.::   |..:.||.|           ...|..:
  Fly   507 SGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCS-----------GLDWQVI 560

Human   287 VQCIERL-----LIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRPVHFQQPQYLHQTHQTS 346
            ..|...:     :|:......:.|:|..|...:.....:.        |.......::.|||.|:
  Fly   561 QPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLIC--------PNIVTDDSHIIQTHTTT 617

Human   347 L-QYRHPTSEQPSCQQIVSTTHTSSYT-------LQTCPAGFQTSVQGLGHMQTGVGMSLAIPVE 403
            : .|......|.:...:.:....|..|       |.|.||......:.||......|....|...
  Fly   618 MDMYDEVLMAQDAAHAMRARIQASPATALRAPESLLTPPASSHKPDEYLGDEGDETGARSGISST 682

Human   404 VKPCLSVSYNRSYQINEHYPCITPCFER 431
            ...|.:.:.|:..:.:.: ..:|.|..|
  Fly   683 TTCCNTAASNKGGKSSSN-NSVTSCSSR 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNJ	XP_016871843.1	CYCLIN_CCNJ-like_rpt1	82..188	CDD:410231	27/111 (24%)
		CYCLIN_CCNJ-like_rpt2	193..293	CDD:410232	20/118 (17%)
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	34/143 (24%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	21/128 (16%)