| Sequence 1: | NP_061947.1 | Gene: | DLL4 / 54567 | HGNCID: | 2910 | Length: | 685 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001073304.1 | Gene: | dll4 / 563920 | ZFINID: | ZDB-GENE-041014-73 | Length: | 683 | Species: | Danio rerio |
| Alignment Length: | 693 | Identity: | 390/693 - (56%) |
|---|---|---|---|
| Similarity: | 478/693 - (68%) | Gaps: | 27/693 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Human 9 SGWALLLLVALWQ---QRAAGSGVFQLQLQEFINERGVLASGRPCEPGCRTFFRVCLKHFQAVVS 70
Human 71 PGPCTFGTVSTPVLGTNSFAVRDDSSGGG--RNPLQLPFNFTWPGTFSLIIEAWHAPGDDLRPEA 133
Human 134 LPPDALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCKKRNDHFGHY 198
Human 199 VCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGT 263
Human 264 CSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSEC 328
Human 329 DSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPN 393
Human 394 FTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDL 458
Human 459 ENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGL 523
Human 524 PP--------SFPWVAVSLGVGLAVLLVLLGMVAVAVRQLRLRRPDDGSR-EAMNNLSDFQKDNL 579
Human 580 IPAAQLKNTNQKKELEVDCGLDKSNCGKQQNHTLDYNLAPGPLGRGTMPGKFPHS-DKSLGEKAP 643
Human 644 L-RLHSEKPECRISAICSPRDSMYQSVCLISEERNECVIATEV 685 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DLL4 | NP_061947.1 | MNNL | 27..88 | CDD:284966 | 40/60 (67%) |
| DSL | 155..217 | CDD:279722 | 39/61 (64%) | ||
| Interaction with Notch1. /evidence=ECO:0000250|UniProtKB:D3ZHH1 | 185..187 | 1/1 (100%) | |||
| Interaction with Notch1. /evidence=ECO:0000250|UniProtKB:D3ZHH1 | 191..195 | 2/3 (67%) | |||
| EGF_CA | 284..322 | CDD:238011 | 29/37 (78%) | ||
| EGF_CA | 327..360 | CDD:238011 | 16/32 (50%) | ||
| EGF_CA | 403..438 | CDD:238011 | 19/34 (56%) | ||
| EGF_CA | <447..476 | CDD:238011 | 16/28 (57%) | ||
| dll4 | NP_001073304.1 | MNNL | 22..83 | CDD:284966 | 40/60 (67%) |
| DSL | 148..210 | CDD:279722 | 39/61 (64%) | ||
| EGF_CA | 277..315 | CDD:238011 | 29/37 (78%) | ||
| EGF_CA | 433..468 | CDD:238011 | 19/34 (56%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 157 | 1.000 | Domainoid score | I16964 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BEE5 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H10411 | |
| Inparanoid | 1 | 1.050 | 821 | 1.000 | Inparanoid score | I3341 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG51332 | |
| OrthoDB | 1 | 1.010 | - | - | D134386at7742 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002026 | |
| OrthoInspector | 1 | 1.000 | - | - | oto42392 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104568 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24044 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X1332 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| ZFIN | 1 | 1.500 | - | - | ||
| 17 | 17.340 | |||||