DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment POU3F4 and nub

DIOPT Version :9

Sequence 1:NP_000298.3 Gene:POU3F4 / 5456 HGNCID:9217 Length:361 Species:Homo sapiens
Sequence 2:NP_001097153.1 Gene:nub / 34669 FlyBaseID:FBgn0085424 Length:961 Species:Drosophila melanogaster


Alignment Length:368 Identity:146/368 - (39%)
Similarity:179/368 - (48%) Gaps:85/368 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    13 SSTSLVHADSAGMQQGSPFRNPQ----KLLQSDYLQGVPSNGHPLGHHWVTSLSDGGPWSSTLAT 73
            |...|:.:.|.|:.|..|....|    :.|....||.:......|                    
  Fly   625 SYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQASQQL-------------------- 669

Human    74 SPLDQQDVKPGREDLQLGAIIHHR------------------------SPHVAHHSPHTNHPNAW 114
            ..|.:|..:...|.|||    :|:                        ||...||  |.:|| ..
  Fly   670 QALQKQQQRQVDEPLQL----NHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHH--HHHHP-LQ 727

Human   115 GASPAPNPSITSSGQPLNVYSQPGFTVSG-MLEHGGLTPPPAAASAQSLHPVLREPPDHGELGSH 178
            ...|:...|:..||.     ..|....|| .:..|..||.|...::.:......||         
  Fly   728 ITPPSSAASLKLSGM-----LTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEP--------- 778

Human   179 HCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFK 243
                 |.|||...:|||||||.||||||||||||.|||||:|.||||.||||||.|||||.||||
  Fly   779 -----SPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFK 838

Human   244 NMCKLKPLLNKWLEEAD---SSTG---SPTSIDKIAAQ----GRKRKKRTSIEVSVKGVLETHFL 298
            |||||||||.|||::||   .:||   .|.::....:.    ||:||||||||.:::|.||..||
  Fly   839 NMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGALEKAFL 903

Human   299 KCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGD 341
            ...||.::||:.|||.|.:||||||||||||||||||:.|..|
  Fly   904 ANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLD 946

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POU3F4NP_000298.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 99..131 10/31 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 144..192 10/47 (21%)
POU 186..260 CDD:197673 59/73 (81%)
Homeobox 281..335 CDD:365835 35/53 (66%)
nubNP_001097153.1 DUF4472 315..>399 CDD:291409
POU 791..855 CDD:197673 53/63 (84%)
Homeobox 886..939 CDD:278475 34/52 (65%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.