Protein Alignment ING3 and png1

DIOPT Version :9

• Sequence 1: NP_061944.2
• Gene: ING3 / 54556
• HGNCID: 14587
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_594080.1
• Gene: png1 / 2543454
• PomBaseID: SPAC3G9.08
• Length: 283
• Species: Schizosaccharomyces pombe
• Alignment Length: 407
• Identity: 98/407 - (24%)
• Similarity: 161/407 - (39%)
• Gaps: 145/407 - (35%)

Human     4 LEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQL---EQRVSEFFMNAKKNKPEWREEQM-AS 64
            |.:||:.::.:|.:.:..|.|:...::.|.:...::   :.::..:..:.....|..:|:.: ::
pombe     9 LSEYLQTLDNVPNETKHIFDEISVKEVAVHDIWKRIQAADSQIQSYIKSHGSLTPHPKEDALYST 73

Human    65 IKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTP 129
            |:::|.||:...:||||||::....:.||:::||..|||         ||
pombe    74 IREEYQKAINIQNEKVQLADRARLGLTRHIKRLDDRLAK---------AG--------------- 114

Human   130 SQPVNNHHAHSHTPVEKRKYNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTA 194
                     |..|..|                         ||
pombe   115 ---------HGFTAAE-------------------------LL---------------------- 123

Human   195 SSNNAYNVNSSQPLGSYNIGSLSSGTGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNND 259
               ||.:..:|.|.|.|:    .||..:...|.|.:::..:||    |||.:|      |.....
pombe   124 ---NAPDYYASSPYGGYS----PSGASSARQTPAPSRSGASTA----GRRRTS------ATTRGA 171

Human   260 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSS 324
            .|.|         |.:|..:|           |.|||.|.|         .|:.|::::::.|.:
pombe   172 IQNG---------VYHSPYTA-----------SLADSGSTR---------GQKVSNATATTQLET 207

Human   325 CSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYG 389
            .:.|:|..:.:|::..   |.|           || :||.|.|.|||:||.|||.:|..||||..
pombe   208 KADSTTPNEMVSEEDM---EED-----------NE-KYCFCQQGSYGQMVACDNANCEREWFHME 257

Human   390 CVGLTEAPKGKWYCPQC 406
            ||||...|:|.|||..|
pombe   258 CVGLKAPPEGTWYCEAC 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ING3	NP_061944.2	ING	3..102	CDD:404028	23/101 (23%)
		TNG2	4..410	CDD:227367	98/407 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..165		3/37 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	286..325		9/38 (24%)
		PHD_ING3	362..406	CDD:277060	26/43 (60%)
png1	NP_594080.1	TNG2	3..278	CDD:227367	98/407 (24%)
		ING	9..111	CDD:289749	23/101 (23%)
		PHD_ING	230..274	CDD:276980	26/43 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	49	1.000	Domainoid score	I3852
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I1743
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		mtm10262
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10333
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.080