| Sequence 1: | NP_001138424.1 | Gene: | SDK2 / 54549 | HGNCID: | 19308 | Length: | 2172 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476899.1 | Gene: | robo1 / 37603 | FlyBaseID: | FBgn0005631 | Length: | 1395 | Species: | Drosophila melanogaster |
| Alignment Length: | 1478 | Identity: | 349/1478 - (23%) |
|---|---|---|---|
| Similarity: | 536/1478 - (36%) | Gaps: | 349/1478 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MWGLLIWTLLAL---HQIRAARAQDDVSPYFKTEPVRTQVHLEGNR-LVLTCMAEGSWPLEFKWL 61
Human 62 H-------NNRELTKFSLE------YRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYM- 112
Human 113 GSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIP----------PSSRIAITLENT 167
Human 168 LVILSTVAP-DAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTS 231
Human 232 EVTLECVANARPLIKLHIIWKKD--GVLLSGGISDHNRR-LTIPNPTGSDAGYYECEAVLRSSSV 293
Human 294 PSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKD-AAVVEVEKLTRF 357
Human 358 RQR--NDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI----APNITRGPLDSTVIDG 416
Human 417 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSR 481
Human 482 GVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRI 546
Human 547 RLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLT 611
Human 612 WTKPFD---GNSPLIRYILE--MSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDV 671
Human 672 GKGQFSKDTERVSLPEEPPTAPPQNVIASGRT---------------NQS-IMIQWQPPPESHQN 720
Human 721 GILKGYIIRYCLAGLPVGYQFKNIT--DADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVT 783
Human 784 EWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTM-VTARP 847
Human 848 NFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP---QLVRTHEDVPGPVGHLSFSEILDT 909
Human 910 SLKVSWQEPGEKNGILTGYRISWEEYNR---------TNTRVTHYLPNVTLEYRVTGLTALTTYT 965
Human 966 IEVAAMTSKGQGQVS-----ASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISR 1025
Human 1026 WLVEAQVGVVGEGEEWLLIHQLSNEPDARS-------MEVPDLNPFTCYSFRMRQVN-------- 1075
Human 1076 IVGTSPPSQPSRKIQTLQAPPD-------------MAPA-----NVSLRTASETSLWLRWMPLPE 1122
Human 1123 MEY----------NGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEW---TEYRVQ 1174
Human 1175 VQAFNAIGSGPWSQTVVGRTRESVPSSGPTN------VSALATTSSSMLVRWSEVPEADRNGLVL 1233
Human 1234 GYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLD 1298
Human 1299 DVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTAN 1346 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SDK2 | NP_001138424.1 | Ig | 27..109 | CDD:299845 | 19/95 (20%) |
| IG_like | 40..109 | CDD:214653 | 17/82 (21%) | ||
| I-set | 120..203 | CDD:254352 | 25/93 (27%) | ||
| Ig | 132..210 | CDD:299845 | 21/88 (24%) | ||
| IG_like | 222..304 | CDD:214653 | 24/84 (29%) | ||
| IGc2 | 233..286 | CDD:197706 | 17/55 (31%) | ||
| I-set | 308..397 | CDD:254352 | 28/91 (31%) | ||
| Ig | 326..394 | CDD:143165 | 22/70 (31%) | ||
| I-set | 402..492 | CDD:254352 | 29/89 (33%) | ||
| Ig | 416..492 | CDD:299845 | 24/75 (32%) | ||
| Ig | 502..586 | CDD:299845 | 11/83 (13%) | ||
| IG_like | 502..586 | CDD:214653 | 11/83 (13%) | ||
| FN3 | 590..681 | CDD:238020 | 29/95 (31%) | ||
| FN3 | 693..786 | CDD:238020 | 23/110 (21%) | ||
| FN3 | 794..890 | CDD:238020 | 28/99 (28%) | ||
| FN3 | 895..983 | CDD:238020 | 15/101 (15%) | ||
| FN3 | 993..1087 | CDD:238020 | 24/108 (22%) | ||
| FN3 | 1099..1194 | CDD:238020 | 26/112 (23%) | ||
| FN3 | 1201..1290 | CDD:238020 | 16/94 (17%) | ||
| FN3 | 1301..1394 | CDD:238020 | 11/46 (24%) | ||
| FN3 | 1400..1484 | CDD:238020 | |||
| FN3 | 1503..1616 | CDD:238020 | |||
| FN3 | 1626..1719 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1707..1729 | ||||
| FN3 | 1724..1805 | CDD:238020 | |||
| FN3 | 1837..1916 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2039..2067 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2098..2172 | ||||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 | 2166..2172 | ||||
| robo1 | NP_476899.1 | Ig | 56..151 | CDD:299845 | 21/97 (22%) |
| I-set | 56..150 | CDD:254352 | 20/96 (21%) | ||
| I-set | 157..251 | CDD:254352 | 26/98 (27%) | ||
| Ig2_Robo | 159..251 | CDD:143201 | 25/96 (26%) | ||
| I-set | 255..341 | CDD:254352 | 26/91 (29%) | ||
| Ig3_Robo | 272..341 | CDD:143202 | 22/73 (30%) | ||
| IG_like | 351..436 | CDD:214653 | 25/85 (29%) | ||
| Ig | 362..444 | CDD:299845 | 25/81 (31%) | ||
| I-set | 445..531 | CDD:254352 | 32/124 (26%) | ||
| IGc2 | 459..521 | CDD:197706 | 20/65 (31%) | ||
| FN3 | 549..637 | CDD:238020 | 28/91 (31%) | ||
| FN3 | 673..762 | CDD:238020 | 20/90 (22%) | ||
| fn3 | 770..855 | CDD:278470 | 26/89 (29%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||