| Sequence 1: | NP_001138424.1 | Gene: | SDK2 / 54549 | HGNCID: | 19308 | Length: | 2172 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001261571.1 | Gene: | Dscam4 / 2769008 | FlyBaseID: | FBgn0263219 | Length: | 1935 | Species: | Drosophila melanogaster |
| Alignment Length: | 1872 | Identity: | 429/1872 - (22%) |
|---|---|---|---|
| Similarity: | 700/1872 - (37%) | Gaps: | 496/1872 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Human 48 CMAEGSWPLEFKWLHNNRELTKFS-LEY-----RYMITSLDRTHAGFYRCIVRNRMGALLQRQTE 106
Human 107 VQVA-----YMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIA----I 162
Human 163 TLENTLV----ILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKN 223
Human 224 TSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGS----------D 278
Human 279 AGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVV--DIPCQ-AKGVPPPSI 340
Human 341 TWYKDAAVV-----EVEKLTRFRQRND--GGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVT 398
Human 399 SIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQK------GE--RILASGSVQLPRFTPL 455
Human 456 ESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRI-----TKPPQDQSVIKGTQASM 515
Human 516 VCGVTHDPRVTIRYIWEKDGATL-----GTESHPRIR---LDRN--GSLHISQTWSGDIGTYTCR 570
Human 571 VISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRY------ILEM 629
Human 630 SENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 694
Human 695 QNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLP--------VGYQFKNITDADVNN 751
Human 752 -----LLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFT 811
Human 812 WNAPSPQFINGINQGYKL--IAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCF 874
Human 875 TTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTN 939
Human 940 TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNI 1004
Human 1005 GPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLN--PFTCY 1067
Human 1068 SFRMRQVNIVGTSPPSQ----PSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGN 1128
Human 1129 PESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS------GPWS 1187
Human 1188 Q-TVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251
Human 1252 --LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSP---------SHPPILERTLDDVPGPPM 1305
Human 1306 GILFPEVRTTSVRLIWQPPAAPNGI-ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPES 1369
Human 1370 VYLFRITAQTRKGWGEAA-EALVVTTE----KRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGL 1429
Human 1430 SPVRYYT------------------------IQTRELPSGRWALHSASVSHNAS----------- 1459
Human 1460 -SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQ 1523
Human 1524 PPAEDKING-ILLGFRIRYRELLYEGLRG-FTLRGI----------------------------- 1557
Human 1558 ---NNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAV---------GEGPS 1610
Human 1611 SPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERV 1675
Human 1676 KTLFLAENSVKLKNLTGYTA----YMVSVAAFNAAGDGPRSTPTQGQTQQAA 1723 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SDK2 | NP_001138424.1 | Ig | 27..109 | CDD:299845 | 15/66 (23%) |
| IG_like | 40..109 | CDD:214653 | 15/66 (23%) | ||
| I-set | 120..203 | CDD:254352 | 23/90 (26%) | ||
| Ig | 132..210 | CDD:299845 | 21/85 (25%) | ||
| IG_like | 222..304 | CDD:214653 | 23/91 (25%) | ||
| IGc2 | 233..286 | CDD:197706 | 18/62 (29%) | ||
| I-set | 308..397 | CDD:254352 | 24/98 (24%) | ||
| Ig | 326..394 | CDD:143165 | 20/77 (26%) | ||
| I-set | 402..492 | CDD:254352 | 28/97 (29%) | ||
| Ig | 416..492 | CDD:299845 | 24/83 (29%) | ||
| Ig | 502..586 | CDD:299845 | 30/93 (32%) | ||
| IG_like | 502..586 | CDD:214653 | 30/93 (32%) | ||
| FN3 | 590..681 | CDD:238020 | 28/96 (29%) | ||
| FN3 | 693..786 | CDD:238020 | 31/105 (30%) | ||
| FN3 | 794..890 | CDD:238020 | 27/97 (28%) | ||
| FN3 | 895..983 | CDD:238020 | 13/87 (15%) | ||
| FN3 | 993..1087 | CDD:238020 | 22/99 (22%) | ||
| FN3 | 1099..1194 | CDD:238020 | 18/101 (18%) | ||
| FN3 | 1201..1290 | CDD:238020 | 23/99 (23%) | ||
| FN3 | 1301..1394 | CDD:238020 | 20/94 (21%) | ||
| FN3 | 1400..1484 | CDD:238020 | 20/119 (17%) | ||
| FN3 | 1503..1616 | CDD:238020 | 24/155 (15%) | ||
| FN3 | 1626..1719 | CDD:238020 | 16/96 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1707..1729 | 5/17 (29%) | |||
| FN3 | 1724..1805 | CDD:238020 | 429/1872 (23%) | ||
| FN3 | 1837..1916 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2039..2067 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2098..2172 | ||||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 | 2166..2172 | ||||
| Dscam4 | NP_001261571.1 | Ig | 31..124 | CDD:416386 | |
| Ig strand A | 32..35 | CDD:409353 | |||
| Ig strand A' | 41..45 | CDD:409353 | |||
| Ig strand B | 48..57 | CDD:409353 | |||
| Ig strand D | 75..78 | CDD:409353 | |||
| Ig strand E | 83..88 | CDD:409353 | |||
| Ig strand F | 101..109 | CDD:409353 | |||
| Ig strand G | 112..124 | CDD:409353 | |||
| Ig | 235..326 | CDD:416386 | |||
| Ig strand A | 235..238 | CDD:409353 | |||
| Ig strand A' | 244..248 | CDD:409353 | |||
| Ig strand B | 251..258 | CDD:409353 | |||
| Ig strand C | 266..271 | CDD:409353 | |||
| Ig strand C' | 276..279 | CDD:409353 | |||
| Ig strand D | 285..289 | CDD:409353 | |||
| Ig strand E | 292..298 | CDD:409353 | |||
| Ig strand F | 305..313 | CDD:409353 | |||
| Ig strand G | 316..326 | CDD:409353 | |||
| IgC2_3_Dscam | 329..417 | CDD:409549 | 15/66 (23%) | ||
| Ig strand B | 347..351 | CDD:409549 | 429/1872 (23%) | ||
| Ig strand C | 360..364 | CDD:409549 | 0/3 (0%) | ||
| Ig strand E | 383..387 | CDD:409549 | 1/3 (33%) | ||
| Ig strand F | 397..402 | CDD:409549 | 2/4 (50%) | ||
| Ig strand G | 410..413 | CDD:409549 | 1/2 (50%) | ||
| IgI_4_Dscam | 422..516 | CDD:409548 | 25/101 (25%) | ||
| Ig strand B | 439..443 | CDD:409548 | 0/3 (0%) | ||
| Ig strand C | 452..456 | CDD:409548 | 2/3 (67%) | ||
| Ig strand E | 482..486 | CDD:409548 | 0/3 (0%) | ||
| Ig strand F | 496..501 | CDD:409548 | 1/4 (25%) | ||
| Ig strand G | 509..512 | CDD:409548 | 1/2 (50%) | ||
| IgI_5_Dscam | 520..607 | CDD:409550 | 26/98 (27%) | ||
| Ig strand B | 536..540 | CDD:409550 | 0/3 (0%) | ||
| Ig strand C | 549..553 | CDD:409550 | 2/5 (40%) | ||
| Ig strand E | 571..575 | CDD:409550 | 1/3 (33%) | ||
| Ig strand F | 586..591 | CDD:409550 | 2/4 (50%) | ||
| Ig strand G | 600..603 | CDD:409550 | 1/2 (50%) | ||
| Ig | 610..703 | CDD:416386 | 25/99 (25%) | ||
| Ig strand A | 611..613 | CDD:409353 | 1/1 (100%) | ||
| Ig strand A' | 620..624 | CDD:409353 | 1/3 (33%) | ||
| Ig strand B | 627..636 | CDD:409353 | 3/8 (38%) | ||
| Ig strand C | 641..648 | CDD:409353 | 3/6 (50%) | ||
| Ig strand C' | 650..652 | CDD:409353 | 0/1 (0%) | ||
| Ig strand D | 659..664 | CDD:409353 | 4/9 (44%) | ||
| Ig strand E | 668..675 | CDD:409353 | 2/6 (33%) | ||
| Ig strand F | 682..690 | CDD:409353 | 3/7 (43%) | ||
| Ig strand G | 693..702 | CDD:409353 | 1/8 (13%) | ||
| IgI_7_Dscam | 706..801 | CDD:409546 | 29/102 (28%) | ||
| Ig strand B | 724..728 | CDD:409546 | 2/3 (67%) | ||
| Ig strand C | 737..741 | CDD:409546 | 2/3 (67%) | ||
| Ig strand E | 766..770 | CDD:409546 | 1/3 (33%) | ||
| Ig strand F | 780..785 | CDD:409546 | 1/4 (25%) | ||
| Ig strand G | 794..797 | CDD:409546 | 0/2 (0%) | ||
| Ig | 818..904 | CDD:416386 | 28/88 (32%) | ||
| putative Ig strand B | 820..827 | CDD:409353 | 1/6 (17%) | ||
| putative Ig strand C | 835..841 | CDD:409353 | 1/8 (13%) | ||
| putative Ig strand C' | 853..856 | CDD:409353 | 1/2 (50%) | ||
| putative Ig strand D | 862..866 | CDD:409353 | 2/3 (67%) | ||
| putative Ig strand E | 868..874 | CDD:409353 | 2/5 (40%) | ||
| putative Ig strand F | 881..889 | CDD:409353 | 3/7 (43%) | ||
| putative Ig strand G | 892..902 | CDD:409353 | 4/9 (44%) | ||
| FN3 | 906..999 | CDD:238020 | 29/100 (29%) | ||
| FN3 | 1006..1110 | CDD:238020 | 31/106 (29%) | ||
| fn3 | 1117..1203 | CDD:394996 | 26/91 (29%) | ||
| FN3 | 1215..1307 | CDD:238020 | 27/162 (17%) | ||
| Ig | <1334..1401 | CDD:416386 | 21/118 (18%) | ||
| Ig strand C | 1345..1349 | CDD:409353 | 2/36 (6%) | ||
| Ig strand D | 1363..1366 | CDD:409353 | 0/2 (0%) | ||
| Ig strand E | 1367..1372 | CDD:409353 | 2/12 (17%) | ||
| Ig strand F | 1380..1388 | CDD:409353 | 1/7 (14%) | ||
| Ig strand G | 1394..1401 | CDD:409353 | 1/6 (17%) | ||
| FN3 | 1405..1494 | CDD:238020 | 23/96 (24%) | ||
| FN3 | 1499..1580 | CDD:238020 | 19/91 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3510 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||