| Sequence 1: | NP_001138424.1 | Gene: | SDK2 / 54549 | HGNCID: | 19308 | Length: | 2172 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001261317.1 | Gene: | zormin / 2769001 | FlyBaseID: | FBgn0052311 | Length: | 3664 | Species: | Drosophila melanogaster |
| Alignment Length: | 2115 | Identity: | 409/2115 - (19%) |
|---|---|---|---|
| Similarity: | 664/2115 - (31%) | Gaps: | 651/2115 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Human 26 PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRY-----MITSLDRTH 85
Human 86 AGFYRCIVRNRMGALLQRQTEVQVAYMGSF--EEGEKH----------------QSVSHGEAAVI 132
Human 133 RAP-RIASFPQPQVTWFRDGRKIPPSSRIAITLEN---TLVILSTVAPDAGRYYVQAVNDKNGDN 193
Human 194 KTSQPITLTVENVGGPADPIAPTIIIPPKN---------TSVVAGTSE-VTLECVANA-RPLIKL 247
Human 248 HIIWKKDGVLLSGGISDHNR------RLTIPNPTGSDAGYY-----------EC--EAVLRSSSV 293
Human 294 PSVVRGAYLSV-----LEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWY---------- 343
Human 344 ------KDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAG--------------- 387
Human 388 ----EVQT----------------STYLAVTSIAPNITRGPLDSTVIDGMSVVL--ACETSGAPR 430
Human 431 PAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWAR 495
Human 496 TRI--------TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNG 552
Human 553 -SLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINL------ 610
Human 611 --------TW---TKPF------------DGNSPLIRYILEMSE--NNAPWTVLLASVDPKATSV 650
Human 651 TVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPP 715
Human 716 ESHQN------------GILKGYII--RYCLAGLPVGYQFKNITDADVNNLLLEDLII-----WT 761
Human 762 NYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQG 826
Human 827 YKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSV-----------LCF------ 874
Human 875 -----------------TTPGDGP---------RSTPQLVRTHEDV------------------- 894
Human 895 -PGPVG-----HLSF----------------SEILDTSLKVSWQEPGEKNGILTGYRIS--WEEY 935
Human 936 NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLG 1000
Human 1001 ISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPD-ARSMEVPDLNPF 1064
Human 1065 TCYSFRMRQVNIVGTSPPSQPS-RKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGN 1128
Human 1129 PESVGYKIKYSRSD---GHGK--TLSHVVQDRVERDYTIEDLEEWTEYRVQVQAF------NAIG 1182
Human 1183 SGPWSQT--------------VVGRTRESVPSSGP---TNVSALAT-----TSSSMLVRWSEVPE 1225
Human 1226 ADRNGL--------------VLGY-----------KVMYKEKDSDTQPRFWLVEGNSSRSAQLTG 1265
Human 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGI 1330
Human 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTE 1395
Human 1396 KRDR-PQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNAS 1459
Human 1460 SFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQA--------APDEA--PTILSVTPHT 1514
Human 1515 -----TTSVLIRWQPPA---------------EDKINGILLGFRIR-----YRELLYEGLRGFTL 1554
Human 1555 -----RGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQ 1614
Human 1615 EVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLD--SQNGDIQGYKIYFWEAQRGNLTERVKT 1677
Human 1678 LFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742
Human 1743 SWEAPQFPN--------------GIL---EGYRLV 1760 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SDK2 | NP_001138424.1 | Ig | 27..109 | CDD:299845 | 20/86 (23%) |
| IG_like | 40..109 | CDD:214653 | 17/73 (23%) | ||
| I-set | 120..203 | CDD:254352 | 22/102 (22%) | ||
| Ig | 132..210 | CDD:299845 | 21/81 (26%) | ||
| IG_like | 222..304 | CDD:214653 | 23/111 (21%) | ||
| IGc2 | 233..286 | CDD:197706 | 16/72 (22%) | ||
| I-set | 308..397 | CDD:254352 | 27/139 (19%) | ||
| Ig | 326..394 | CDD:143165 | 20/118 (17%) | ||
| I-set | 402..492 | CDD:254352 | 17/91 (19%) | ||
| Ig | 416..492 | CDD:299845 | 14/77 (18%) | ||
| Ig | 502..586 | CDD:299845 | 22/84 (26%) | ||
| IG_like | 502..586 | CDD:214653 | 22/84 (26%) | ||
| FN3 | 590..681 | CDD:238020 | 18/121 (15%) | ||
| FN3 | 693..786 | CDD:238020 | 21/111 (19%) | ||
| FN3 | 794..890 | CDD:238020 | 25/138 (18%) | ||
| FN3 | 895..983 | CDD:238020 | 23/110 (21%) | ||
| FN3 | 993..1087 | CDD:238020 | 20/95 (21%) | ||
| FN3 | 1099..1194 | CDD:238020 | 24/119 (20%) | ||
| FN3 | 1201..1290 | CDD:238020 | 21/121 (17%) | ||
| FN3 | 1301..1394 | CDD:238020 | 17/92 (18%) | ||
| FN3 | 1400..1484 | CDD:238020 | 12/83 (14%) | ||
| FN3 | 1503..1616 | CDD:238020 | 27/144 (19%) | ||
| FN3 | 1626..1719 | CDD:238020 | 16/94 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1707..1729 | 5/21 (24%) | |||
| FN3 | 1724..1805 | CDD:238020 | 12/54 (22%) | ||
| FN3 | 1837..1916 | CDD:238020 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2039..2067 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 2098..2172 | ||||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 | 2166..2172 | ||||
| zormin | NP_001261317.1 | SPEC | 126..332 | CDD:238103 | |
| SPEC | <504..641 | CDD:295325 | |||
| COG1340 | 960..1298 | CDD:224259 | |||
| RILP-like | <1190..1315 | CDD:304877 | |||
| MAP7 | 1233..1365 | CDD:283355 | |||
| I-set | 1390..1479 | CDD:254352 | |||
| IGc2 | 1403..1469 | CDD:197706 | |||
| I-set | 1491..1580 | CDD:254352 | |||
| IGc2 | 1504..1570 | CDD:197706 | |||
| I-set | 1589..1675 | CDD:254352 | 22/89 (25%) | ||
| Ig | 1605..1675 | CDD:299845 | 17/72 (24%) | ||
| I-set | 1702..1786 | CDD:254352 | 22/84 (26%) | ||
| Ig | 1713..1786 | CDD:299845 | 19/73 (26%) | ||
| I-set | 1811..1902 | CDD:254352 | 19/91 (21%) | ||
| Ig | 1828..1892 | CDD:143165 | 15/64 (23%) | ||
| I-set | 1927..2015 | CDD:254352 | 23/104 (22%) | ||
| IGc2 | 1940..2005 | CDD:197706 | 16/80 (20%) | ||
| I-set | 2142..2231 | CDD:254352 | 24/90 (27%) | ||
| Ig | 2158..2231 | CDD:299845 | 20/74 (27%) | ||
| I-set | 2238..2325 | CDD:254352 | 16/88 (18%) | ||
| Ig | 2254..2324 | CDD:299845 | 13/71 (18%) | ||
| I-set | 3566..3655 | CDD:254352 | |||
| Ig | 3583..3650 | CDD:143165 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||