DRSC/TRiP Functional Genomics Resources

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Protein Alignment POU3F1 and pdm2

DIOPT Version :9

Sequence 1:NP_002690.3 Gene:POU3F1 / 5453 HGNCID:9214 Length:451 Species:Homo sapiens
Sequence 2:NP_001285877.1 Gene:pdm2 / 34673 FlyBaseID:FBgn0004394 Length:893 Species:Drosophila melanogaster


Alignment Length:327 Identity:133/327 - (40%)
Similarity:165/327 - (50%) Gaps:72/327 - (22%)


- Green bases have known domain annotations that are detailed below.


Human   139 PAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPS 203
            |::||.|..|...|..|         |........||.:|......|.:.       .:.||:.|
  Fly   611 PSLSPVPRHSKSQQRTP---------PNSMTANSLGMSSAVMTPNTPSMQ-------QQPQLQQS 659

Human   204 PPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIK 268
            .|            ....||..|:|          .:..|.|.|:....::||||||.|||||||
  Fly   660 TP------------KPTSGLTVASA----------MAKLEQSPEETTDLEELEQFAKTFKQRRIK 702

Human   269 LGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDS----SSGSPTN 329
            |||||.|||||:|.||||.||||||.|||||.|||||||||||||.||||:.||    |.|...|
  Fly   703 LGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFN 767

Human   330 LDKIAAQ---------GRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRV 385
            ::.:.:.         ||:||||||||..|:..||..||...||::.||:.|::.|.::|||:||
  Fly   768 INTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRV 832

Human   386 WFCNRRQKEKRMTPAAGAGHP---PMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHTLP 447
            |||||||||||:.|:.....|   |:.. :|.|.                 ||.||:..|.....
  Fly   833 WFCNRRQKEKRINPSLDLDSPTGTPLSS-HAFGY-----------------PPQALNMSHMQMEG 879

Human   448 GS 449
            ||
  Fly   880 GS 881

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POU3F1NP_002690.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 69..114
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..154 6/14 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..253 11/66 (17%)
POU 247..321 CDD:197673 57/73 (78%)
Homeobox 342..396 CDD:395001 31/53 (58%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 395..451 14/58 (24%)
pdm2NP_001285877.1 POU 691..755 CDD:197673 54/63 (86%)
Homeobox 789..842 CDD:278475 30/52 (58%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3802
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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