Protein Alignment POU3F1 and nub

DIOPT Version :10

• Sequence 1: NP_002690.3
• Gene: POU3F1 / 5453
• HGNCID: 9214
• Length: 451
• Species: Homo sapiens
• Sequence 2: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Alignment Length: 447
• Identity: 164/447 - (36%)
• Similarity: 211/447 - (47%)
• Gaps: 84/447 - (18%)

Human    15 GAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLG------AGAGHPVGLAHPQW 73
            |.|.|.|  :..|||||||||.|..:.:|     :..|:....:.      |.||  :|:.:|
  Fly   541 GCGSTTP--NSMAAAAAAAAAVASTMGSG-----ISPLLALPGMSSPQAQLAAAG--LGMNNP-- 594

Human    74 LPTGGGGGGDWAG----------------GPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAA 122
            |.||.....|:|.                ..::|..::|..|..:.|.........|:.:.|...
  Fly   595 LLTGSLSPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQL 659

Human   123 HAGAAWAQGSTA------------HHLGPAMSPSPGASGGHQ-PQPLGLYAQAAYPGGGGGGLAG 174
            .|.:..:|...|            ..|...|:..|.:|..|. ..|:.:.:.|:.|
  Fly   660 QALSQASQQLQALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSP--------- 715

Human   175 MLAAGGGGAGPGLHHALHEDGHEAQL-EPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHP-----G 233
                      ..|||..|   |..|: .||....|...|.........|...:.....|     .
  Fly   716 ----------QQLHHHHH---HPLQITPPSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVA 767

Human   234 AGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEA 298
            :.....:.||.|.|:....::||||||.||||||||||||.|||||:|.||||.||||||.||||
  Fly   768 SAAAARAAGEPSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEA 832

Human   299 LQLSFKNMCKLKPLLNKWLEETDSSSGSPTNL-DKIAAQ---------GRKRKKRTSIEVGVKGA 353
            |.|||||||||||||.|||::.|.:..:...: |..|.|         ||:||||||||..::||
  Fly   833 LNLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEIIGRRRKKRTSIETTIRGA 897

Human   354 LESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDD 410
            ||..||...||::.|||.|||.|.:||||||||||||||||||:.|:..:.....||
  Fly   898 LEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRINPSLDSPTGADDD 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU3F1	NP_002690.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/5 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..114		10/60 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..154		7/39 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..253		16/72 (22%)
		POU	247..321	CDD:197673	56/73 (77%)
		Homeodomain	340..396	CDD:459649	39/55 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	395..451		5/16 (31%)
nub	NP_001097153.1	POU	791..855	CDD:197673	53/63 (84%)
		Homeodomain	884..940	CDD:459649	39/55 (71%)