Protein Alignment POU2F2 and pdm2

DIOPT Version :9

• Sequence 1: XP_016882373.1
• Gene: POU2F2 / 5452
• HGNCID: 9213
• Length: 723
• Species: Homo sapiens
• Sequence 2: NP_001285877.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 211/550 - (38%)
• Similarity: 260/550 - (47%)
• Gaps: 135/550 - (24%)

Human    24 LDSPSEHTDTERNGPDTNHQNPQNKT-SPFSVSPTGPSTKVGILSGLHLTF------WGPGPC-- 79
            :|.|.|.:..|:..|:..|..|.||. ...|.|||.|| .:..||....:|      .|.. |
  Fly   419 VDPPKEPSIYEQPAPNGRHCRPANKVMRHMSNSPTPPS-PLRSLSDCGKSFEEEELELGEN-CEM 481

Human    80 -----------------------LSPPQIKAEDPSGDSAPAAPLPPQP---AQPHLPQAQLMLTG 118
                                   |:||..:..:...:...|:..||||   |...:.||..:...
  Fly   482 PQNLSSKRQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQALQLQLH 546

Human   119 SQLAGLTALMP--------AQQQLLLQQAQAQLLAAAVQQSSAAAAANAAAAAAAASASSSTSSS 175
            |.:..:..|.|        |.|.||....||.....|:||.......:...:.:...|.|...|.
  Fly   547 SYIEMVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSP 611

Human   176 SSSSASSSTSQPPASSGGGDLPPPQPASQPPGTPQLTLSQPIQLTAQDIQQLLQLQQLVLVPGHH 240
            |.|                  |.|:.:.....||      |..:||..    |.:...|:.|.
  Fly   612 SLS------------------PVPRHSKSQQRTP------PNSMTANS----LGMSSAVMTPN-- 646

Human   241 LQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQP 305
                                 ||::.|.||..|.   |.:|.:|| |.|.....|
  Fly   647 ---------------------TPSMQQQPQLQQS---TPKPTSGL-TVASAMAKL---------- 676

Human   306 PKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 370
                  ...|||.:|||||||||:|||||||||||||||||||||||||||||||||||||||||
  Fly   677 ------EQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 735

Human   371 SFKNMCKLKPLLEKWLNDAETMSVDS--SLPSPNQLSSP-SLGFDGLPGRRRKKRTSIETNVRFA 432
            ||||||||||||:|||.||::....|  .:.:.|.::|. |...:.:.||||||||||||.||..
  Fly   736 SFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTT 800

Human   433 LEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSP-GKPAS--- 493
            |||:||.|.|||||||..::|:|:|:||||||||||||||||||||   :..|.|| |.|.|
  Fly   801 LEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINP---SLDLDSPTGTPLSSHA 862

Human   494 --YSP------HMVTPQGGAGTLPLSQASS 515
              |.|      || ..:||:|:...|..||
  Fly   863 FGYPPQALNMSHM-QMEGGSGSFCGSSISS 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU2F2	XP_016882373.1	None
pdm2	NP_001285877.1	POU	691..755	CDD:197673	60/63 (95%)
		Homeobox	789..842	CDD:278475	39/52 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4687
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003004
OrthoInspector	1	1.000	-	-		mtm8655
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.910