Protein Alignment POU2F1 and pdm2

DIOPT Version :9

• Sequence 1: XP_011507955.1
• Gene: POU2F1 / 5451
• HGNCID: 9212
• Length: 769
• Species: Homo sapiens
• Sequence 2: NP_001285877.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Alignment Length: 464
• Identity: 187/464 - (40%)
• Similarity: 238/464 - (51%)
• Gaps: 91/464 - (19%)

Human   107 SQQPSQPSQQPSVQ---AAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSA 168
            |..|:.||...|:.   .:..:.:|.|.........|:..:|...|........|..|...:..|
  Fly   449 SNSPTPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSKRQARELDSELENEVLDLAPPPKRLA 513

Human   169 SQQHSAAGATISASAATPMTQIPLSQPIQIA-QDLQQLQQLQQQNLNLQQFVLV--------HPT 224
            .:|.....|:::.           .||:..| :::.|..|||     |..::.:        .|.
  Fly   514 EEQEEEKVASVNP-----------PQPVAFAPEEMHQALQLQ-----LHSYIEMVRQLAPEAFPN 562

Human   225 TNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQS-----------QPSIT-----LTS 273
            .|| ..||::..:   .|.|.|.| .|.|:.||.:.:.|.|           .||::     ..|
  Fly   563 PNL-ATQFLLQNS---LQALAQFQ-ALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKS 622

Human   274 QPATPTRTIAA-------------TP-IQTLPQ-SQSTPKRID-----------TPSLEEPSDLE 312
            |..||..::.|             || :|..|| .|||||...           ..|.||.:|||
  Fly   623 QQRTPPNSMTANSLGMSSAVMTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLE 687

Human   313 ELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLN 377
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||.
  Fly   688 ELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLE 752

Human   378 DAENLSSDSS------LSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEIT 436
            ||::..:.|.      .:..|.|:|.....|.|||||||||||.:|..|||:||.|.|||||||:
  Fly   753 DADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEIS 817

Human   437 MIADQLNMEKEVIRVWFCNRRQKEKRINP----------PSSGGTSSSPIKAIFPSPTSLVATTP 491
            .::::|||:||||||||||||||||||||          |.|......|.:|:..|...:...:.
  Fly   818 QLSERLNMDKEVIRVWFCNRRQKEKRINPSLDLDSPTGTPLSSHAFGYPPQALNMSHMQMEGGSG 882

Human   492 SLVTSSAAT 500
            |...||.::
  Fly   883 SFCGSSISS 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POU2F1	XP_011507955.1	POU	306..380	CDD:197673	69/73 (95%)
		Homeobox	408..461	CDD:278475	38/52 (73%)
pdm2	NP_001285877.1	POU	691..755	CDD:197673	61/63 (97%)
		Homeobox	789..842	CDD:278475	38/52 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	142	1.000	Domainoid score	I4687
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8655
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.910