DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RHOF and chw-1

DIOPT Version :9

Sequence 1:	NP_061907.2	Gene:	RHOF / 54509	HGNCID:	15703	Length:	211	Species:	Homo sapiens
Sequence 2:	NP_505686.1	Gene:	chw-1 / 184848	WormBaseID:	WBGene00009059	Length:	207	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	61/187 - (32%)
Similarity:	104/187 - (55%)	Gaps:	12/187 - (6%)

- Green bases have known domain annotations that are detailed below.

Human    18 KELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDR 82
            |.||.:.||:...||||:::.|:...:|.:|.|:.|:.::..|.|..|.:.|.|:|||||..:|.
Worm     8 KCLKCIFVGNAAVGKTSMIVSYTTNVYPHNYVPTAFDNFSVVVLVDKKPIRLQLHDTAGQSSFDT 72

Human    83 LRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRA 147
            ||||.|.:..:.:|.|.|::..|:::|...|:||||....|..::|:|.:.|.|   .|:|.
Worm    73 LRPLCYTDADVFVIVYSVVDLQSFEDVSHHWYPEVTKRNPGTKLILVGTQADQR---WQVRG--- 131

Human   148 AQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKK 204
               ..:|.::|.:..::: .|.:.||||..:.|::.:|..|....|..  |..|:|:
Worm   132 ---NTVTQLRGKALADRL-GAEFFECSALTQHNLKQMFDAAILAGLEG--KKNREKR 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RHOF	NP_061907.2	Rho4_like	17..211	CDD:206704	61/187 (33%)
		RHO	22..195	CDD:197554	55/172 (32%)
		Effector region. /evidence=ECO:0000255	48..56		3/7 (43%)
chw-1	NP_505686.1	Wrch_1	10..172	CDD:133330	56/171 (33%)
chw-1	NP_505686.1	RHO	12..174	CDD:197554	54/171 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820