DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC13 and CG13029

DIOPT Version :9

Sequence 1:	NP_061901.2	Gene:	ZDHHC13 / 54503	HGNCID:	18413	Length:	622	Species:	Homo sapiens
Sequence 2:	NP_648928.1	Gene:	CG13029 / 39886	FlyBaseID:	FBgn0036670	Length:	288	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	63/316 - (19%)
Similarity:	117/316 - (37%)	Gaps:	94/316 - (29%)

- Green bases have known domain annotations that are detailed below.

Human   305 AIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVYLPTAFLLSSVFWIFMTWFILFFP 369
            |:|::|            :...|||...:|          ..||..:....:|: .:.|.:..|
  Fly    27 AVGFVL------------VGTVLFFSVEMF----------YMLPRIYDTDGLFF-KIAWLMALF- 67

Human   370 DLAGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASE----EEKKVNIITLAETGSLDFRTFCTS 430
                      .:::::..:...::..:......|..:    |||.:             ..||..
  Fly    68 ----------IVYNLLGNMLACHRNSSAVTSLPKDRQIPCPEEKHL-------------WHFCDH 109

Human   431 CLIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSS 495
            |.:..|.||.||.||.||:.|.|.||::|..|:|..|:.|:.:|..::.:       ||.:.|::
  Fly   110 CQMLVPPRSWHCKVCECCILRRDHHCIFTATCVGHTNYRYFFWFTVYMHI-------GSLLSLAT 167

Human   496 HCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQL------FQIAFL-----G 549
            |......::.:...            |:::    ||| ..||.|..:      ..|:|:     .
  Fly   168 HVNLLIIDEQIRRQ------------YVVL----HFS-RFFLFLKPMSCELIALNISFIINIYAC 215

Human   550 LTSHERISLQKQSKHMKQTLSLRKTP----YNLGFMQNLADFF-QCGCFGLVKPCV 600
            :.|...:..|..:.::..|.   .||    ||.|.:.|...|. :.|.:..:.|.:
  Fly   216 ILSLIMLGYQIPALYLNTTF---YTPKDYRYNQGLLGNFMAFMGKRGLWTFISPSI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC13	NP_061901.2	ANK 1. /evidence=ECO:0000250\|UniProtKB:Q8IUH5	43..78
		ANK	79..192	CDD:238125
		ANK repeat	81..112	CDD:293786
		ANK 2. /evidence=ECO:0000255	81..110
		ANK repeat	114..146	CDD:293786
		ANK 3. /evidence=ECO:0000255	115..144
		ANKYR	<145..271	CDD:223738
		ANK repeat	148..179	CDD:293786
		ANK 4. /evidence=ECO:0000255	148..177
		ANK repeat	181..247	CDD:293786
		ANK 5. /evidence=ECO:0000255	181..211
		ANK 6. /evidence=ECO:0000255	216..245
		ANK 7. /evidence=ECO:0000255	249..277
		zf-DHHC	423..559	CDD:307600	36/146 (25%)
CG13029	NP_648928.1	zf-DHHC	100..236	CDD:279823	40/175 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810