DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RBM47 and Rbm47

DIOPT Version :9

Sequence 1:	NP_001092104.1	Gene:	RBM47 / 54502	HGNCID:	30358	Length:	593	Species:	Homo sapiens
Sequence 2:	NP_001005882.1	Gene:	Rbm47 / 305340	RGDID:	1359713	Length:	590	Species:	Rattus norvegicus

Alignment Length:	595	Identity:	560/595 - (94%)
Similarity:	573/595 - (96%)	Gaps:	7/595 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     1 MTAEDSTAAMSSDSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGP 65
            |||||||.||:||...|||.||||||||||||||||||||||||:||||||||||||||||||||
  Rat     1 MTAEDSTTAMNSDPTVGSSTKVPEGVAGAPNEAALLALMERTGYNMVQENGQRKYGGPPPGWEGP 65

Human    66 HPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRE 130
            |||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||
  Rat    66 HPQRGCEVFVGKIPRDVYEDELVPVFETVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRE 130

Human   131 LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRG 195
            ||||||||||||||||||||||||||||||||||.||||||||||||||:|||||||||||||||
  Rat   131 LNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRGEILEEIAKVTEGVLNVIVYASAADKMKNRG 195

Human   196 FAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTED 260
            |||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||:
  Rat   196 FAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMQTVKILYVRNLMIETTEE 260

Human   261 TIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYS 325
            |||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 TIKRSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYS 325

Human   326 RYQKAAR-GGGAAEA-AQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGN 388
            ||||||: |||:||| |||||||||||||||||||||||||||||||||||.|||||||||||||
  Rat   326 RYQKAAKGGGGSAEAVAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKTGSIRGRGRGAAGN 390

Human   389 RAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEIPTVNPVAIKPGTVAIPAIGAQY 453
            |.|||||||||||||||||||||||||||||||||||||||||..||||||||||||||||||||
  Rat   391 RTPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEISAVNPVAIKPGTVAIPAIGAQY 455

Human   454 SMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPI 518
            |||.||||||:||||||||:||||||||||||||:  |||||||||||||||.||||||||||||
  Rat   456 SMFQAAPAPKIIEDGKIHTMEHMISPIAVQPDPAT--AAAAAAAAAAAAVIPAVSTPPPFQGRPI 518

Human   519 TPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAMYGGYAGYIPQAFPAAAIQ 583
            ||||||||||.|||||||||||||||||||||||||||||  ||||:||||||||||||| ||:|
  Rat   519 TPVYTVAPNVPRIPTAGIYGASYVPFAAPATATIATLQKN--AAAAVYGGYAGYIPQAFP-AALQ 580

Human   584 VPIPDVYQTY 593
            |||.||||||
  Rat   581 VPIHDVYQTY 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM47	NP_001092104.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		17/23 (74%)
RBM47	NP_001092104.1	hnRNP-R-Q	21..593	CDD:273732	544/573 (95%)
Rbm47	NP_001005882.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		18/24 (75%)
Rbm47	NP_001005882.1	hnRNP-R-Q	11..590	CDD:273732	549/583 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83691083
Domainoid	1	1.000	512	1.000	Domainoid score	I6847
eggNOG	1	0.900	-	-		E1_KOG0117
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H36932
Inparanoid	1	1.050	1121	1.000	Inparanoid score	I4573
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG43401
OrthoDB	1	1.010	-	-		D119371at32523
OrthoFinder	1	1.000	-	-		FOG0000581
OrthoInspector	1	1.000	-	-		oto144018
orthoMCL	1	0.900	-	-		OOG6_105311
Panther	1	1.100	-	-	LDO	PTHR21245
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X331
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.270