Protein Alignment PON1 and YBR053C

DIOPT Version :10

• Sequence 1: NP_000437.3
• Gene: PON1 / 5444
• HGNCID: 9204
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_009609.1
• Gene: YBR053C / 852342
• SGDID: S000000257
• Length: 358
• Species: Saccharomyces cerevisiae
• Alignment Length: 172
• Identity: 40/172 - (23%)
• Similarity: 63/172 - (36%)
• Gaps: 51/172 - (29%)

Human   202 WSYVVYYSPSEVRVVAEGFDF-ANGINISPDGKYVYI------------------AELLAHKIHV 247
            |.||:.||..........:.. :|..|:||||||:|:                  .:||||||.:
Yeast   127 WEYVILYSECPELSTDRAYKLRSNDGNVSPDGKYIYVGLMSDFPFDLEPIGCLLRVDLLAHKIEL 191

Human   248 ------------YEKHANWTLTPLKSLDF-------------NTLVDNISVDPETGDLWVGCHPN 287
                        :::....|:....||:|             :.|:|   |.......:....|:
Yeast   192 VWNCLLIPNAIHWDESDQKTMYVTDSLNFTIWKCPGGDLLKRDELID---VKNSNNQSFESPEPD 253

Human   288 GMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQ 329
            |..|:|  |::...|..|.|  .:....||......||.:|:
Yeast   254 GSAIWF--SKDGKHSGFLFI--TVWSTSKVQMFDLTNGKLLK 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PON1	NP_000437.3	YvrE	83..318	CDD:442613	36/159 (23%)
		Arylesterase	168..253	CDD:334656	20/81 (25%)
YBR053C	NP_009609.1	SGL	27..318	CDD:462480	40/172 (23%)
		WD40 repeat	150..186	CDD:293791	10/35 (29%)
		WD40 repeat	199..248	CDD:293791	7/51 (14%)
		WD40 repeat	259..294	CDD:293791	10/37 (27%)