Protein Alignment PON1 and Pon1

DIOPT Version :10

• Sequence 1: NP_000437.3
• Gene: PON1 / 5444
• HGNCID: 9204
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_114466.1
• Gene: Pon1 / 84024
• RGDID: 620062
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 355
• Identity: 286/355 - (80%)
• Similarity: 322/355 - (90%)
• Gaps: 0/355 - (0%)

Human     1 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFI 65
            ||||:.|||:|:.|||::||:|||||||||.|||.||:||||.||||||.|:||||||||||.|.
  Rat     1 MAKLLGLTLVGLVLALYKNHRSSYQTRLNAFREVTPVDLPNCTLVKGIEAGAEDLEILPNGLTFF 65

Human    66 SSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLL 130
            |:||||||||||:|:.|||||||||||::|.|.||.|.|:..|:|||||||||||.||||.:|||
  Rat    66 STGLKYPGIKSFDPSKPGKILLMDLNEKEPAVSELAIMGNTLDMSSFNPHGISTFIDEDNTVYLL 130

Human   131 VVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWE 195
            ||:|||:.||||:|||||||:||||||||.|:|||::|||.|||||.||.||||||.||||:|||
  Rat   131 VVSHPDSSSTVEVFKFQEEERSLLHLKTITHELLPSINDIAAVGPESFYATNDHYFADPYLRSWE 195

Human   196 MYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLK 260
            |||||:||.||||||.:|||||:||||||||.||.||||||||||||||||||||||||||||||
  Rat   196 MYLGLSWSNVVYYSPDKVRVVADGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLK 260

Human   261 SLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENG 325
            .|.|:||||||||||.|||||||||||||:||||||||||.|||||||:||:|:||||.||||||
  Rat   261 VLSFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDSENPPGSEVLRIQSILSEDPKVTVVYAENG 325

Human   326 TVLQGSTVASVYKGKLLIGTVFHKALYCEL 355
            |||||:|||:|||||||||||||:||.|:|
  Rat   326 TVLQGTTVAAVYKGKLLIGTVFHRALCCDL 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PON1	NP_000437.3	YvrE	83..318	CDD:442613	191/234 (82%)
		Arylesterase	168..253	CDD:334656	72/84 (86%)
Pon1	NP_114466.1	Arylesterase	168..253	CDD:334656	72/84 (86%)