Protein Alignment PON1 and regucalcin

DIOPT Version :10

• Sequence 1: NP_000437.3
• Gene: PON1 / 5444
• HGNCID: 9204
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_727588.2
• Gene: regucalcin / 32165
• FlyBaseID: FBgn0030362
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 206
• Identity: 48/206 - (23%)
• Similarity: 74/206 - (35%)
• Gaps: 69/206 - (33%)

Human   129 LLVVN----HPDAKSTVELFKFQE-EEKSLLHLKTIRHKLLPNLNDIVAVGPE-HFYGTNDHYFL 187
            :::||    .|.||....||:.|. .||:             .||| ..|.|. .|:|....|..
  Fly    96 VVIVNWDGVSPSAKVVRTLFEVQPLMEKN-------------RLND-AKVDPRGRFFGGTMRYIG 146

Human   188 DPY------LQSWE-------------MYLGLAW----SYVVYYSPSEVRVVAEGFDFANGINIS 229
            |.:      |..||             :..||||    ....|...::..|.:..:||..|:..:
  Fly   147 DEFEFRHGELYRWEAGGQVSVIKGDVGISNGLAWDEKAKKFYYIDTTDYEVKSYDYDFETGVASN 211

Human   230 PDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFY 294
            |  |.::.....:.|.|:                   |.|.:::|.| |:|:|... ||..|:
  Fly   212 P--KVIFNLRKNSPKDHL-------------------LPDGLTIDTE-GNLYVATF-NGATIY-- 251

Human   295 DSENPPASEVL 305
             ..||...::|
  Fly   252 -KVNPNTGKIL 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PON1	NP_000437.3	YvrE	83..318	CDD:442613	48/206 (23%)
		Arylesterase	168..253	CDD:334656	24/108 (22%)
regucalcin	NP_727588.2	SGL	31..290	CDD:462480	48/206 (23%)