Protein Alignment PON1 and Pon1

DIOPT Version :10

• Sequence 1: NP_000437.3
• Gene: PON1 / 5444
• HGNCID: 9204
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_035264.2
• Gene: Pon1 / 18979
• MGIID: 103295
• Length: 355
• Species: Mus musculus
• Alignment Length: 355
• Identity: 292/355 - (82%)
• Similarity: 328/355 - (92%)
• Gaps: 0/355 - (0%)

Human     1 MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFI 65
            ||||:||||:|:.|||::||:|||||||||.|||.||||||||||||||||:||||||||||.|.
Mouse     1 MAKLLALTLVGLVLALYKNHRSSYQTRLNAFREVTPVELPNCNLVKGIETGAEDLEILPNGLTFF 65

Human    66 SSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLL 130
            |:||||||||||:|:.||||||||||:::|.|.||.|.|:..|:||||||||||||||||.:|||
Mouse    66 STGLKYPGIKSFDPSKPGKILLMDLNKKEPAVSELEIIGNTLDISSFNPHGISTFTDEDNTVYLL 130

Human   131 VVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWE 195
            ||||||:.||||:|||||||:||||||||.|:|||::|||.|:|||.||.||||||.||||:|||
Mouse   131 VVNHPDSSSTVEVFKFQEEERSLLHLKTITHELLPSINDIAAIGPESFYATNDHYFADPYLRSWE 195

Human   196 MYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLK 260
            |||||:||.||||||.:|:||||||||||||.||.||||||||||||||||||||||||||||||
Mouse   196 MYLGLSWSNVVYYSPDKVQVVAEGFDFANGIGISLDGKYVYIAELLAHKIHVYEKHANWTLTPLK 260

Human   261 SLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENG 325
            .|:|:||||||||||.|||||||||||||:|||||:||||.||||||||||:|:||:|.||||||
Mouse   261 VLNFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDAENPPGSEVLRIQNILSEDPKITVVYAENG 325

Human   326 TVLQGSTVASVYKGKLLIGTVFHKALYCEL 355
            |||||:||||||||||||||||||||||:|
Mouse   326 TVLQGTTVASVYKGKLLIGTVFHKALYCDL 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PON1	NP_000437.3	YvrE	83..318	CDD:442613	191/234 (82%)
		Arylesterase	168..253	CDD:334656	71/84 (85%)
Pon1	NP_035264.2	Arylesterase	168..253	CDD:334656	71/84 (85%)