Protein Alignment NLGN3 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_851820.1
• Gene: NLGN3 / 54413
• HGNCID: 14289
• Length: 848
• Species: Homo sapiens
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 855
• Identity: 718/855 - (83%)
• Similarity: 772/855 - (90%)
• Gaps: 7/855 - (0%)

Human     1 MWLRLGPPSLSLSPKPTVGRSLC-LTLWFLSLA---LRASTQAPAPTVNTHFGKLRGARVPLPSE 61
            |||.:....|.|..:....|..| ::||.|...   :....|...|||||.:||||||||||.||
Zfish    24 MWLAMRKKRLLLHHQDCCSRRACNISLWILVFCWCMMLVRGQGYYPTVNTQYGKLRGARVPLHSE 88

Human    62 ILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTAN 126
            ||||||||||||||.||:|||||||||||.|||||:|||||.||||||||.||||:|:|:|||.|
Zfish    89 ILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPVCPQNIHNAVPEIMMPIWFTFN 153

Human   127 LDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDED 191
            ||||||.||:.||||||||:||||||||||||||.||||||||||||:.:|||||||:|||||||
Zfish   154 LDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICRKGGTHSKKQGEDLSDNDGDED 218

Human   192 EDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNY 256
            |||||:|||||||||||||||||||||||||:|||||||||||||:|||||||||||||||||||
Zfish   219 EDIRDTGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNFRVGVLGFLSTGDQAAKGNY 283

Human   257 GLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW 321
            |||||||||||:||||.:||||..|||||||||||||||||||||||||||.|||||||||||||
Zfish   284 GLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSW 348

Human   322 AVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDD 386
            ||||||||||.|||:|||||||||:|||||||:|||:||||||||||||||||||||||||||||
Zfish   349 AVNYQPVKYTRLLAEKVGCNVLDTLDMVDCLRKKSARELVEQDIQPARYHVAFGPVIDGDVIPDD 413

Human   387 PEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLR 451
            |||||||||||||||||||||||||:|||.|||.||||||.|||:|||:|||:||||||||||||
Zfish   414 PEILMEQGEFLNYDIMLGVNQGEGLRFVENVVDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLR 478

Human   452 ETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKP 516
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   479 ETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKP 543

Human   517 AWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFI 581
            ||||||||||||||||:||:||||||||||||||:||||||||||||||||||||||||||||||
Zfish   544 AWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNKPVPQDTKFI 608

Human   582 HTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTK 646
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
Zfish   609 HTKANRFEEVAWSKYNPQDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTK 673

Human   647 VPPPDTTHSSHITRRPNGKTW--STKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELS 709
            |||.:||.:|..|:|||||.|  :||||.:||||::|:.:..|||:::.|||:||||||||||||
Zfish   674 VPPLETTQNSLSTKRPNGKAWPFNTKRPPMSPAYNSESGKEQWNGEEEPGPLVVENPRDYSTELS 738

Human   710 VTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGA-APEEELAALQLGPTHH 773
            ||||||||||||||||||||||||||||||...||||.|.....::.. |||||:.:||:..|||
Zfish   739 VTIAVGASLLFLNVLAFAALYYRKDKRRQEQHPQPSPPRATTTNDVNRHAPEEEIMSLQVNQTHH 803

Human   774 ECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTG 838
            ||:|||..|.|||.:||||.|||||||||||||||||||||||||||:..|||||||.|||||||
Zfish   804 ECDAGPTGDPLRLASLPDYALTLRRSPDDIPLMTPNTITMIPNSLVGMPNLHPYNTFTAGFNSTG 868

Human   839 LPHSHSTTRV 848
            ||||||||||
Zfish   869 LPHSHSTTRV 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NLGN3	NP_851820.1	COesterase	40..624	CDD:395084	534/583 (92%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..195		20/24 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..694		27/50 (54%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	534/581 (92%)