Protein Alignment POLR2F and Polr2F

DIOPT Version :10

• Sequence 1: NP_001288059.1
• Gene: POLR2F / 5435
• HGNCID: 9193
• Length: 158
• Species: Homo sapiens
• Sequence 2: NP_524910.1
• Gene: Polr2F / 48312
• FlyBaseID: FBgn0003275
• Length: 131
• Species: Drosophila melanogaster
• Alignment Length: 388
• Identity: 74/388 - (19%)
• Similarity: 128/388 - (32%)
• Gaps: 156/388 - (40%)

Human   380 EVGKPSDPLTREQDANK-INYMYAQYVKNTMEP---LNIPDV---TKDKRF---PWT-------- 426
            :|..|:..:|  ||:.| ::|.::       ||   |..||.   ::.:||   |.|
  Fly   468 DVSPPTSNVT--QDSPKEMSYQHS-------EPSPALPSPDASVPSEHERFARSPPTLVFTEQST 523

Human   427 -------NENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQFLEA 484
                   ||.:.||.|            ..:::.||.|        .:|..::.|:.:||.....
  Fly   524 EDAPESPNEVVHHVQT------------EAQQSPVIDV--------HSTHVVEHFDTHDESPQSP 568

Human   485 FVIFCGLGIQNTQMYE------------AVERAMAKQMVTLEVLSYHASAAEE------------ 525
            .:...|    ..:.||            ...:|.::.:....|.|.|:|.|.|
  Fly   569 VLSVHG----GEEGYEDHHDEAPVLSVHTDHKAHSEDVPQSPVQSVHSSHASEHIDEAPQSPVPS 629

Human   526 -------ETRELQALSAAV-----VPSAQTLKITDFSFS------DFELSD-LETALCTIRMFTD 571
                   |..|.:||.:.|     ||||::..:...:|.      .|..|: ::.||
  Fly   630 VHSSHASEHIEQEALPSPVASERDVPSAESPLVQSENFEHHAEVHSFHASEHIDEAL-------- 686

Human   572 LNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLAL 636
            .:.||:....|:                      .|..::......|.::..:|:..|
  Fly   687 PSPVQSVHSSHD----------------------HHDRSSPVASEPAARSPSVQSSRT------- 722

Human   637 LIAALSHDLDHRG-----VNNSYIQRSEH-------PLA-QLYCHSIMEHHHFDQCLMILNSP 686
                 |...:|||     .:::....|||       |:. |...||.....||:...::.:||
  Fly   723 -----SEHFEHRGEVPQSPSSNQFHSSEHIEEARQSPVTNQESVHSPHASEHFEHREVVPHSP 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POLR2F	NP_001288059.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		RNA_pol_Rpb6	<26..>100	CDD:449344
Polr2F	NP_524910.1	PLN00152	27..130	CDD:177755