Protein Alignment POLR2E and Polr2E

DIOPT Version :10

• Sequence 1: XP_011526372.1
• Gene: POLR2E / 5434
• HGNCID: 9192
• Length: 211
• Species: Homo sapiens
• Sequence 2: NP_610630.1
• Gene: Polr2E / 36160
• FlyBaseID: FBgn0033571
• Length: 210
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 178/210 - (84%)
• Similarity: 190/210 - (90%)
• Gaps: 1/210 - (0%)

Human     1 MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQSGDKPSEGRPRRTDLTVLVAHN 65
            ||||.|||:||:||||||||.|||||||||||||||||:||...||||||.||.|:||.||||||
  Fly     1 MDDEAETYKLWRIRKTIMQLSHDRGYLVTQDELDQTLEQFKEMFGDKPSEKRPARSDLIVLVAHN 65

Human    66 DDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQF 130
            ||||||||||||||||:||||||.||.|||||||.||::|||.||||||||||||||||||||||
  Fly    66 DDPTDQMFVFFPEEPKIGIKTIKTYCTRMQEENIHRAIVVVQGGMTPSAKQSLVDMAPKYILEQF 130

Human   131 LQQELLINITEHELVPEHVVMTKEEVTELLARYSKLRENQLPRIQAGDPVARYFGIKRGQVVKII 195
            |:.|||||||||||||||||||.||..|||:|| ||:||.|.|||||||||||||:|||||||||
  Fly   131 LESELLINITEHELVPEHVVMTVEEKQELLSRY-KLKENMLMRIQAGDPVARYFGLKRGQVVKII 194

Human   196 RPSETAGRYITYRLV 210
            |.||||||||:||||
  Fly   195 RSSETAGRYISYRLV 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POLR2E	XP_011526372.1	PLN03111	1..210	CDD:215582	176/208 (85%)
Polr2E	NP_610630.1	PLN03111	1..210	CDD:215582	178/210 (85%)