Protein Alignment GDAP1 and GstD10

DIOPT Version :9

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_001287302.1
• Gene: GstD10 / 59240
• FlyBaseID: FBgn0042206
• Length: 210
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 49/261 - (18%)
• Similarity: 86/261 - (32%)
• Gaps: 77/261 - (29%)

Human    28 LYHWTHSFSSQKVRLVIAEKALKCE---EHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89
            ||:...|...:.|  ::..|||..|   :..::....|...|.::::|....:|.|......:.|
  Fly     3 LYYRPGSAPCRSV--LMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWE 65

Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPA 154
            :..|:.||.:.:          .|:...:|:                            |....|
  Fly    66 SRAIMVYLVEKY----------GKDDKLFPK----------------------------DVQKQA 92

Human   155 YATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV 219
            ....|:...:|..   .|..:|        |...|..|| |..:.:|.|.::...:.|...|
  Fly    93 LINQRLYFDMGTL---YKSFSE--------YYYPQIFLK-KPANEENYKKIEVAFEFLNTFL--- 142

Human   220 ETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVL 284
                         || |.:..|..::|||::...|:......||..:.:.|..|     :||...
  Fly   143 -------------EG-QTYSAGGDYSLADIAFLATVSTFDVAGFDFKRYANVAR-----WYENAK 188

Human   285 K 285
            |
  Fly   189 K 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	16/72 (22%)
		GST_C_GDAP1	179..289	CDD:198336	24/107 (22%)
		Required for mitochondrial localization	320..358
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	17/73 (23%)
		PLN02473	3..196	CDD:166114	49/261 (19%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	29/135 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154505
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840