Protein Alignment GDAP1 and gdap1

DIOPT Version :10

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_001018511.1
• Gene: gdap1 / 553702
• ZFINID: ZDB-GENE-050522-424
• Length: 362
• Species: Danio rerio
• Alignment Length: 321
• Identity: 253/321 - (78%)
• Similarity: 285/321 - (88%)
• Gaps: 1/321 - (0%)

Human    25 KLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89
            ||||||||.|||||||||.||||.|:||::||||||||||||||||||.|||||||:|..::||:
Zfish    39 KLILYHWTQSFSSQKVRLAIAEKGLQCEDYDVSLPLSEHNEPWFMRLNPTGEVPVLVHDNHVICD 103

Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPA 154
            .|||:|||||.|.||:||:|:|::.|.||.||||||||||||.|||||||||||||:||||.|||
Zfish   104 PTQIMDYLEQNFCDEQTPKLIPEEGSTYYHRVQHYRELLDSLQMDAYTHGCILHPEITVDSHIPA 168

Human   155 YATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV 219
            ||||.||:|||||||||||||.|||||::||||||:||||||.||||:|||||:|||||.|||||
Zfish   169 YATTHIRTQIGNTESELKKLAVENPDLKDAYIAKQRRLKSKLFDHDNMKYLKKLLDELENVLDQV 233

Human   220 ETELQRRNEETPEEG-QQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERV 283
            |||||||:||||||| ||.||||:.|::||||||||||||||||.:||.||||.|.|||||||||
Zfish   234 ETELQRRSEETPEEGSQQAWLCGDFFSIADVSLAVTLHRLKFLGLSRRYWGNGMRVNLETYYERV 298

Human   284 LKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRL 344
            |.|.||.:|||||||||||||||||||||||:||..:|.||:|||:.|..|.||:.|:|||
Zfish   299 LDRPTFRRVLGHVNNILISAVLPTAFRVAKKKAPAFVGATLLVGLIGGATYLAFIYFKKRL 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	56/71 (79%)
		GST_C_GDAP1	179..289	CDD:198336	89/110 (81%)
		Required for mitochondrial localization	320..358		14/25 (56%)
gdap1	NP_001018511.1	GST_N_GDAP1	40..112	CDD:239350	56/71 (79%)
		GST_C_family	193..304	CDD:470672	89/110 (81%)