DRSC/TRiP Functional Genomics Resources

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Protein Alignment GDAP1 and GstE7

DIOPT Version :9

Sequence 1:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens
Sequence 2:NP_611329.1 Gene:GstE7 / 37112 FlyBaseID:FBgn0063493 Length:223 Species:Drosophila melanogaster


Alignment Length:271 Identity:55/271 - (20%)
Similarity:95/271 - (35%) Gaps:69/271 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    25 KLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89
            |||||....|...:.|:|.:|...:..|..:|:....|:....|::.|....||.|....:.|.:
  Fly     3 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWD 67

Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPA 154
            :..||.||...:          .|....||:....|.::|..          ||.|   ..:|.|
  Fly    68 SHAIIAYLVSKY----------GKTDSLYPKDLLQRAVVDQR----------LHFE---SGVIFA 109

Human   155 YATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV 219
            .|...|...:                    :..||..:..:..|     .:.::.|.|||.|   
  Fly   110 NALRSITKPL--------------------FAGKQTMIPKERYD-----AIIEVYDFLEKFL--- 146

Human   220 ETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVL 284
                          ....::.|...|:||.|:..|:..|:.  |.:.:  ..|.|.:..:::|:.
  Fly   147 --------------AGNDYVAGNQLTIADFSIISTVSSLEV--FVKVD--TTKYPRIAAWFKRLQ 193

Human   285 KRKTFNKVLGH 295
            |...:.:..|:
  Fly   194 KLPYYEEANGN 204

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 20/71 (28%)
GST_C_GDAP1 179..289 CDD:198336 20/109 (18%)
Required for mitochondrial localization 320..358
GstE7NP_611329.1 GstA 4..196 CDD:223698 53/260 (20%)
GST_N_Delta_Epsilon 4..77 CDD:239343 21/72 (29%)
GST_C_Delta_Epsilon 91..209 CDD:198287 30/173 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154573
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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